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    YKT6 palmitoyltransferase YKT6 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853638, updated on 9-Dec-2024

    Summary

    Official Symbol
    YKT6
    Official Full Name
    palmitoyltransferase YKT6
    Primary source
    SGD:S000001679
    Locus tag
    YKL196C
    See related
    AllianceGenome:SGD:S000001679; FungiDB:YKL196C; VEuPathDB:YKL196C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables SNAP receptor activity and palmitoyltransferase activity. Involved in Golgi vesicle transport and organelle fusion. Located in several cellular components, including Golgi apparatus; endosome; and fungal-type vacuole. Part of SNARE complex. Is active in autophagosome membrane. Orthologous to human YKT6 (YKT6 v-SNARE homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See YKT6 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (74932..75534, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene AAA family ATPase peroxin 1 Neighboring gene tRNA-Asn Neighboring gene Mia40p Neighboring gene threonine--tRNA ligase MST1

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables SNAP receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables palmitoyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of SNARE complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of SNARE complex IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in autophagosome membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in bounding membrane of organelle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol HDA PubMed 
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in fungal-type vacuole IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    palmitoyltransferase YKT6
    NP_012725.1
    • Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within Golgi, endocytic trafficking to vacuole, and vacuolar fusion; membrane localization due to prenylation at carboxy-terminus; targeted to vacuole via AP-3 pathway; human homolog YKT6 can complement yeast ykt6 mutant

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      74932..75534 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179762.1NP_012725.1  TPA: palmitoyltransferase YKT6 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012725.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VX04, P36015
      UniProtKB/TrEMBL
      A6ZZC9, B3LQQ9, B5VLW8, C7GJ13, C8ZBY0, G2WHJ6, N1P0I2
      Conserved Domains (1) summary
      COG5143
      Location:3200
      SNC1; Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]