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    FIN1 Fin1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851708, updated on 9-Dec-2024

    Summary

    Official Symbol
    FIN1
    Official Full Name
    Fin1p
    Primary source
    SGD:S000002537
    Locus tag
    YDR130C
    See related
    AllianceGenome:SGD:S000002537; FungiDB:YDR130C; VEuPathDB:YDR130C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables microtubule binding activity. A structural constituent of cytoskeleton. Involved in several processes, including cytoskeleton organization; deactivation of mitotic spindle assembly checkpoint; and protein localization to kinetochore. Located in cytoskeleton; kinetochore; and nucleus. Part of protein phosphatase type 1 complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See FIN1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (715747..716622, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Mtc5p Neighboring gene fimbrin Neighboring gene uncharacterized protein Neighboring gene Mrx16p

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    located_in astral microtubule PubMed 
    located_in cytoplasm PubMed 
    located_in cytoplasm  
    located_in cytoskeleton  
    located_in intermediate filament PubMed 
    located_in kinetochore PubMed 
    located_in mitotic spindle PubMed 
    located_in nucleus PubMed 
    located_in nucleus  
    part_of protein phosphatase type 1 complex PubMed 
    located_in spindle microtubule PubMed 
    located_in spindle pole  
    located_in spindle pole body PubMed 
    located_in spindle pole body PubMed 

    General protein information

    Preferred Names
    Fin1p
    NP_010415.1
    • Spindle pole body-related intermediate filament protein; forms cell cycle-specific filaments between spindle pole bodies in dividing cells; localizes to poles and microtubules of spindle during anaphase and contributes to spindle stability; involved in Glc7p localization and regulation; relative distribution to the nucleus increases upon DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      715747..716622 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180438.1 → NP_010415.1  TPA: Fin1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010415.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSB6, Q03898
      UniProtKB/TrEMBL
      B5VG28, C7GIN8, C8Z546
      Conserved Domains (1) summary
      pfam17300
      Location:15 → 283
      FIN1; Filament protein FIN1
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