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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850463, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000000696
    Locus tag
    YCR099C
    See related
    AllianceGenome:SGD:S000000696; FungiDB:YCR099C; VEuPathDB:YCR099C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to several human genes including SORCS1 (sortilin related VPS10 domain containing receptor 1); SORCS2 (sortilin related VPS10 domain containing receptor 2); and SORCS3 (sortilin related VPS10 domain containing receptor 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_001135.5 (300832..301299, complement)

    Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene tRNA-Thr Neighboring gene Git1p Neighboring gene Ema35p Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001135.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The complete DNA sequence of yeast chromosome III. Oliver SG, et al. Nature, 1992 May 7. PMID 1574125
    2. Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins. Tonikian R, et al. PLoS Biol, 2009 Oct. PMID 19841731, Free PMC Article
    3. Association of yeast Upf1p with direct substrates of the NMD pathway. Johansson MJ, et al. Proc Natl Acad Sci U S A, 2007 Dec 26. PMID 18087042, Free PMC Article
    4. Global analysis of protein phosphorylation in yeast. Ptacek J, et al. Nature, 2005 Dec 1. PMID 16319894
    5. The Chromatin Remodeler ISW1 Is a Quality Control Factor that Surveys Nuclear mRNP Biogenesis. Babour A, et al. Cell, 2016 Nov 17. PMID 27863241

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001135.5 Reference assembly

      Range
      300832..301299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178806.1 → NP_010023.1  TPA: uncharacterized protein YCR099C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010023.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRA0, P25657
      UniProtKB/TrEMBL
      B3LUF2, B5VF29, C8Z4I6
      Conserved Domains (1) summary
      smart00602
      Location:3 → 130
      VPS10; VPS10 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25657.1

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