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    Zc2hc1c zinc finger, C2HC-type containing 1C [ Mus musculus (house mouse) ]

    Gene ID: 72350, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zc2hc1cprovided by MGI
    Official Full Name
    zinc finger, C2HC-type containing 1Cprovided by MGI
    Primary source
    MGI:MGI:1919600
    See related
    Ensembl:ENSMUSG00000045064 AllianceGenome:MGI:1919600
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam164c; 2810002I04Rik
    Summary
    Predicted to enable metal ion binding activity. Is expressed in pancreas epithelium. Orthologous to human ZC2HC1C (zinc finger C2HC-type containing 1C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 5.9), genital fat pad adult (RPKM 1.7) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zc2hc1c in Genome Data Viewer
    Location:
    12 D1- D2; 12 39.63 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (85321020..85346132)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (85274243..85299361)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene mutL homolog 3 Neighboring gene microRNA 6938 Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene STARR-seq mESC enhancer starr_32767 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:86621244-86621431 Neighboring gene acylphosphatase 1 Neighboring gene STARR-positive B cell enhancer ABC_E7161 Neighboring gene STARR-seq mESC enhancer starr_32769 Neighboring gene NIMA (never in mitosis gene a)-related expressed kinase 9 Neighboring gene STARR-seq mESC enhancer starr_32770 Neighboring gene STARR-seq mESC enhancer starr_32772 Neighboring gene transmembrane p24 trafficking protein 10 Neighboring gene STARR-seq mESC enhancer starr_32773

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Breslow DK, et al. Nat Genet, 2018 Mar. PMID 29459677, Free PMC Article
    2. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger C2HC domain-containing protein 1C
    Names
    family with sequence similarity 164, member C
    protein FAM164C

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172414.4 → NP_766002.2  zinc finger C2HC domain-containing protein 1C

      See identical proteins and their annotated locations for NP_766002.2

      Status: VALIDATED

      Source sequence(s)
      AC159237, AK032455, AK036602, BX525619
      Consensus CDS
      CCDS26056.1
      UniProtKB/Swiss-Prot
      Q8CCG1, Q8CCM8
      UniProtKB/TrEMBL
      Q8CB75
      Related
      ENSMUSP00000051664.5, ENSMUST00000059341.5
      Conserved Domains (2) summary
      pfam03938
      Location:192 → 262
      OmpH; Outer membrane protein (OmpH-like)
      pfam13913
      Location:491 → 513
      zf-C2HC_2; zinc-finger of a C2HC-type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      85321020..85346132
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516270.3 → XP_006516333.1  zinc finger C2HC domain-containing protein 1C isoform X1

      See identical proteins and their annotated locations for XP_006516333.1

      UniProtKB/Swiss-Prot
      Q8CCG1, Q8CCM8
      UniProtKB/TrEMBL
      Q8CB75
      Conserved Domains (2) summary
      pfam03938
      Location:192 → 262
      OmpH; Outer membrane protein (OmpH-like)
      pfam13913
      Location:491 → 513
      zf-C2HC_2; zinc-finger of a C2HC-type

    2. XM_006516269.4 → XP_006516332.1  zinc finger C2HC domain-containing protein 1C isoform X1

      See identical proteins and their annotated locations for XP_006516332.1

      UniProtKB/Swiss-Prot
      Q8CCG1, Q8CCM8
      UniProtKB/TrEMBL
      Q8CB75
      Conserved Domains (2) summary
      pfam03938
      Location:192 → 262
      OmpH; Outer membrane protein (OmpH-like)
      pfam13913
      Location:491 → 513
      zf-C2HC_2; zinc-finger of a C2HC-type

    3. XM_036157623.1 → XP_036013516.1  zinc finger C2HC domain-containing protein 1C isoform X1

      UniProtKB/Swiss-Prot
      Q8CCG1, Q8CCM8
      UniProtKB/TrEMBL
      Q8CB75
      Conserved Domains (2) summary
      pfam03938
      Location:192 → 262
      OmpH; Outer membrane protein (OmpH-like)
      pfam13913
      Location:491 → 513
      zf-C2HC_2; zinc-finger of a C2HC-type
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CCG1.1 GenPept UniProtKB/Swiss-Prot:Q8CCG1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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