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    Mast4 microtubule associated serine/threonine kinase family member 4 [ Mus musculus (house mouse) ]

    Gene ID: 328329, updated on 27-Dec-2024

    Summary

    Official Symbol
    Mast4provided by MGI
    Official Full Name
    microtubule associated serine/threonine kinase family member 4provided by MGI
    Primary source
    MGI:MGI:1918885
    See related
    Ensembl:ENSMUSG00000034751 AllianceGenome:MGI:1918885
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0303; 4930420O11Rik
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization and intracellular signal transduction. Predicted to be located in cytoplasm. Is expressed in brain; thymus primordium; and ventral grey horn. Used to study Sertoli cell-only syndrome. Orthologous to human MAST4 (microtubule associated serine/threonine kinase family member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 6.5), bladder adult (RPKM 6.3) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mast4 in Genome Data Viewer
    Location:
    13 D1; 13 54.94 cM
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (102868996..103471607, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (102732486..103335099, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr13:103468634-103468935 Neighboring gene STARR-positive B cell enhancer ABC_E7271 Neighboring gene STARR-positive B cell enhancer ABC_E1887 Neighboring gene STARR-positive B cell enhancer ABC_E7272 Neighboring gene STARR-positive B cell enhancer ABC_E10811 Neighboring gene STARR-seq mESC enhancer starr_35508 Neighboring gene predicted gene, 41046 Neighboring gene STARR-seq mESC enhancer starr_35509 Neighboring gene STARR-positive B cell enhancer ABC_E3097 Neighboring gene RIKEN cDNA 1700099I09 gene Neighboring gene CD180 antigen Neighboring gene predicted gene 17160 Neighboring gene STARR-seq mESC enhancer starr_35511 Neighboring gene STARR-seq mESC enhancer starr_35515 Neighboring gene STARR-positive B cell enhancer ABC_E3098 Neighboring gene predicted gene, 30106 Neighboring gene predicted gene, 30050 Neighboring gene fibrillarin pseudogene Neighboring gene STARR-seq mESC enhancer starr_35516 Neighboring gene STARR-seq mESC enhancer starr_35518 Neighboring gene STARR-seq mESC enhancer starr_35519 Neighboring gene predicted gene 5454 Neighboring gene ribosomal protein L21 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1) 
    • Endonuclease-mediated (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 3-phosphoinositide-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables Rho-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables eukaryotic translation initiation factor 2alpha kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS121 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AT120 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AXS139 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2BS14 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2BS36 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S10 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S28 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S57 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T11 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T3 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T45 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H4S1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribosomal protein S6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    microtubule-associated serine/threonine-protein kinase 4
    NP_780380.2
    XP_006517764.1
    XP_006517765.1
    XP_006517766.1
    XP_006517767.1
    XP_006517768.1
    XP_006517769.1
    XP_006517770.1
    XP_011242974.1
    XP_011242975.1
    XP_011242976.1
    XP_017171016.1
    XP_017171017.1
    XP_017171018.1
    XP_017171019.1
    XP_017171020.1
    XP_017171021.1
    XP_030103167.1
    XP_030103168.1
    XP_030103169.1
    XP_030103170.1
    XP_036013969.1
    XP_036013970.1
    XP_036013971.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175171.3NP_780380.2  microtubule-associated serine/threonine-protein kinase 4

      See identical proteins and their annotated locations for NP_780380.2

      Status: VALIDATED

      Source sequence(s)
      AC112791, AC114827, AC124387, AC165290, AC167975, AC239606
      Consensus CDS
      CCDS49349.1
      UniProtKB/Swiss-Prot
      E9QAH7, Q3UVE7, Q62489, Q6ZQE0, Q811L6, Q8BME3
      Related
      ENSMUSP00000128464.2, ENSMUST00000167058.8
      Conserved Domains (4) summary
      smart00220
      Location:568841
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd00992
      Location:11441222
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:567846
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:256529
      DUF1908; Domain of unknown function (DUF1908)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      102868996..103471607 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315531.2XP_017171020.1  microtubule-associated serine/threonine-protein kinase 4 isoform X5

      Conserved Domains (3) summary
      cd00992
      Location:11471225
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:570849
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:256532
      DUF1908; Domain of unknown function (DUF1908)
    2. XM_017315530.2XP_017171019.1  microtubule-associated serine/threonine-protein kinase 4 isoform X4

      Conserved Domains (3) summary
      cd00992
      Location:11591237
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:582861
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:268544
      DUF1908; Domain of unknown function (DUF1908)
    3. XM_017315529.2XP_017171018.1  microtubule-associated serine/threonine-protein kinase 4 isoform X3

      Conserved Domains (3) summary
      cd00992
      Location:11721250
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:595874
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:281557
      DUF1908; Domain of unknown function (DUF1908)
    4. XM_017315528.2XP_017171017.1  microtubule-associated serine/threonine-protein kinase 4 isoform X2

      Conserved Domains (3) summary
      cd00992
      Location:11811259
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:604883
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:293566
      DUF1908; Domain of unknown function (DUF1908)
    5. XM_017315532.2XP_017171021.1  microtubule-associated serine/threonine-protein kinase 4 isoform X6

      Conserved Domains (3) summary
      cd00992
      Location:11171195
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:607886
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:293569
      DUF1908; Domain of unknown function (DUF1908)
    6. XM_017315527.2XP_017171016.1  microtubule-associated serine/threonine-protein kinase 4 isoform X1

      Conserved Domains (3) summary
      cd00992
      Location:11841262
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:607886
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:293569
      DUF1908; Domain of unknown function (DUF1908)
    7. XM_036158077.1XP_036013970.1  microtubule-associated serine/threonine-protein kinase 4 isoform X22

      Conserved Domains (3) summary
      cd00992
      Location:878956
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:368647
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:57330
      DUF1908; Domain of unknown function (DUF1908)
    8. XM_006517705.5XP_006517768.1  microtubule-associated serine/threonine-protein kinase 4 isoform X17

      Conserved Domains (3) summary
      cd00992
      Location:9451023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:368647
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:57330
      DUF1908; Domain of unknown function (DUF1908)
    9. XM_006517704.5XP_006517767.1  microtubule-associated serine/threonine-protein kinase 4 isoform X16

      Conserved Domains (3) summary
      cd00992
      Location:9481026
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:371650
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:57333
      DUF1908; Domain of unknown function (DUF1908)
    10. XM_030247309.2XP_030103169.1  microtubule-associated serine/threonine-protein kinase 4 isoform X13

      UniProtKB/TrEMBL
      A0A0A6YXG1
      Related
      ENSMUSP00000141977.3, ENSMUST00000194446.7
      Conserved Domains (3) summary
      cd00992
      Location:9571035
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:380659
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:69342
      DUF1908; Domain of unknown function (DUF1908)
    11. XM_006517702.5XP_006517765.1  microtubule-associated serine/threonine-protein kinase 4 isoform X12

      Conserved Domains (3) summary
      cd00992
      Location:9601038
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:383662
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:69345
      DUF1908; Domain of unknown function (DUF1908)
    12. XM_030247307.2XP_030103167.1  microtubule-associated serine/threonine-protein kinase 4 isoform X9

      UniProtKB/TrEMBL
      A0A668KMA1
      Related
      ENSMUSP00000159269.2, ENSMUST00000239261.2
      Conserved Domains (3) summary
      cd00992
      Location:9701048
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:393672
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:82355
      DUF1908; Domain of unknown function (DUF1908)
    13. XM_036158076.1XP_036013969.1  microtubule-associated serine/threonine-protein kinase 4 isoform X8

      Conserved Domains (3) summary
      cd00992
      Location:9731051
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:396675
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:82358
      DUF1908; Domain of unknown function (DUF1908)
    14. XM_006517701.5XP_006517764.1  microtubule-associated serine/threonine-protein kinase 4 isoform X7

      Conserved Domains (3) summary
      cd00992
      Location:9851063
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:408687
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:94370
      DUF1908; Domain of unknown function (DUF1908)
    15. XM_006517706.4XP_006517769.1  microtubule-associated serine/threonine-protein kinase 4 isoform X18

      Conserved Domains (3) summary
      cd00992
      Location:9401018
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:363642
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:49325
      DUF1908; Domain of unknown function (DUF1908)
    16. XM_030247308.2XP_030103168.1  microtubule-associated serine/threonine-protein kinase 4 isoform X11

      Conserved Domains (3) summary
      cd00992
      Location:9641042
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:387666
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:76349
      DUF1908; Domain of unknown function (DUF1908)
    17. XM_011244672.3XP_011242974.1  microtubule-associated serine/threonine-protein kinase 4 isoform X10

      UniProtKB/TrEMBL
      E9QPR4
      Related
      ENSMUSP00000096808.4, ENSMUST00000099202.10
      Conserved Domains (3) summary
      cd00992
      Location:9671045
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:390669
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:76352
      DUF1908; Domain of unknown function (DUF1908)
    18. XM_030247310.2XP_030103170.1  microtubule-associated serine/threonine-protein kinase 4 isoform X19

      Conserved Domains (3) summary
      cd00992
      Location:9371015
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:360639
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:49322
      DUF1908; Domain of unknown function (DUF1908)
    19. XM_011244673.4XP_011242975.1  microtubule-associated serine/threonine-protein kinase 4 isoform X15

      UniProtKB/TrEMBL
      E9PWX8
      Related
      ENSMUSP00000131651.2, ENSMUST00000171791.8
      Conserved Domains (3) summary
      cd00992
      Location:9521030
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:375654
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:64337
      DUF1908; Domain of unknown function (DUF1908)
    20. XM_006517703.5XP_006517766.1  microtubule-associated serine/threonine-protein kinase 4 isoform X14

      Conserved Domains (3) summary
      cd00992
      Location:9551033
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:378657
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:64340
      DUF1908; Domain of unknown function (DUF1908)
    21. XM_011244674.4XP_011242976.1  microtubule-associated serine/threonine-protein kinase 4 isoform X21

      Conserved Domains (3) summary
      cd00992
      Location:885963
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:375654
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:64337
      DUF1908; Domain of unknown function (DUF1908)
    22. XM_036158078.1XP_036013971.1  microtubule-associated serine/threonine-protein kinase 4 isoform X23

      Conserved Domains (3) summary
      cd00992
      Location:798876
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:221500
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:1183
      DUF1908; Domain of unknown function (DUF1908)
    23. XM_006517707.4XP_006517770.1  microtubule-associated serine/threonine-protein kinase 4 isoform X20

      Conserved Domains (3) summary
      cd00992
      Location:9371015
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd05609
      Location:360639
      STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
      pfam08926
      Location:46322
      DUF1908; Domain of unknown function (DUF1908)