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    Chst12 carbohydrate sulfotransferase 12 [ Mus musculus (house mouse) ]

    Gene ID: 59031, updated on 3-Dec-2024

    Summary

    Official Symbol
    Chst12provided by MGI
    Official Full Name
    carbohydrate sulfotransferase 12provided by MGI
    Primary source
    MGI:MGI:1929064
    See related
    Ensembl:ENSMUSG00000036599 AllianceGenome:MGI:1929064
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C4S-2; C4ST2
    Summary
    Predicted to enable chondroitin 4-sulfotransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process and dermatan sulfate biosynthetic process. Predicted to be located in Golgi membrane. Is expressed in several structures, including alimentary system; clavicle; naris; telencephalon; and viscerocranium. Orthologous to human CHST12 (carbohydrate sulfotransferase 12). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 35.3), lung adult (RPKM 29.2) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Chst12 in Genome Data Viewer
    Location:
    5 G2; 5 79.04 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (140491398..140510993)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (140505569..140525238)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 3, subunit B Neighboring gene microRNA 7038 Neighboring gene STARR-seq mESC enhancer starr_14711 Neighboring gene kinesin family member 19B Neighboring gene STARR-positive B cell enhancer ABC_E2181 Neighboring gene STARR-positive B cell enhancer ABC_E11306 Neighboring gene predicted gene, 38728 Neighboring gene STARR-positive B cell enhancer ABC_E10361 Neighboring gene STARR-seq mESC enhancer starr_14715 Neighboring gene uncharacterized LOC118568761 Neighboring gene predicted gene 42808 Neighboring gene STARR-seq mESC enhancer starr_14717 Neighboring gene predicted gene, 52800

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1)  1 citation
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chondroitin 4-sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables chondroitin 4-sulfotransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in carbohydrate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chondroitin sulfate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chondroitin sulfate biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in dermatan sulfate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in dermatan sulfate biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in proteoglycan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    carbohydrate sulfotransferase 12
    Names
    chondroitin 4-O-sulfotransferase 2
    chondroitin 4-sulfotransferase 2
    NP_001412644.1
    NP_067503.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001425715.1NP_001412644.1  carbohydrate sulfotransferase 12

      Status: VALIDATED

      Source sequence(s)
      AC117602
      UniProtKB/Swiss-Prot
      Q3TCX9, Q99LL3, Q9JJS3
      UniProtKB/TrEMBL
      Q3TQH4
    2. NM_021528.4NP_067503.3  carbohydrate sulfotransferase 12

      See identical proteins and their annotated locations for NP_067503.3

      Status: VALIDATED

      Source sequence(s)
      AC117602
      Consensus CDS
      CCDS19820.1
      UniProtKB/Swiss-Prot
      Q3TCX9, Q99LL3, Q9JJS3
      UniProtKB/TrEMBL
      Q3TQH4
      Related
      ENSMUSP00000041663.9, ENSMUST00000043050.9
      Conserved Domains (1) summary
      pfam03567
      Location:165410
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      140491398..140510993
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)