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    Zcwpw2 zinc finger, CW type with PWWP domain 2 [ Mus musculus (house mouse) ]

    Gene ID: 100039681, updated on 27-Nov-2024

    Summary

    Official Symbol
    Zcwpw2provided by MGI
    Official Full Name
    zinc finger, CW type with PWWP domain 2provided by MGI
    Primary source
    MGI:MGI:1921888
    See related
    Ensembl:ENSMUSG00000032443 AllianceGenome:MGI:1921888
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930430K04Rik
    Summary
    Predicted to enable methylated histone binding activity. Predicted to be active in nucleus. Orthologous to human ZCWPW2 (zinc finger CW-type and PWWP domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Genomic context

    See Zcwpw2 in Genome Data Viewer
    Location:
    9 F3; 9 69.83 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (117752903..117869927, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (117923835..118040859, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RNA binding motif, single stranded interacting protein Neighboring gene predicted gene, 39450 Neighboring gene predicted gene, 26614 Neighboring gene STARR-seq mESC enhancer starr_25450 Neighboring gene predicted gene, 50606 Neighboring gene STARR-positive B cell enhancer ABC_E3864 Neighboring gene STARR-positive B cell enhancer ABC_E2921 Neighboring gene STARR-positive B cell enhancer mm9_chr9:117962449-117962749 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:118059288-118059397 Neighboring gene 5-azacytidine induced gene 2 Neighboring gene C-X9-C motif containing 1 Neighboring gene predicted gene, 17399

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Clone Names

    • MGC129466, MGC141053

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables methylated histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    zinc finger CW-type PWWP domain protein 2 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001378466.1NP_001365395.1  zinc finger CW-type PWWP domain protein 2 homolog

      Status: VALIDATED

      Source sequence(s)
      AC157475, AC165253
      UniProtKB/Swiss-Prot
      A0A5F8MP94, Q08EN7
      Related
      ENSMUSP00000158867.2, ENSMUST00000238919.2
      Conserved Domains (2) summary
      pfam07496
      Location:1462
      zf-CW; CW-type Zinc Finger
      cl02554
      Location:82155
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      117752903..117869927 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)