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    Gnat3 G protein subunit alpha transducin 3 [ Mus musculus (house mouse) ]

    Gene ID: 242851, updated on 27-Nov-2024

    Summary

    Official Symbol
    Gnat3provided by MGI
    Official Full Name
    G protein subunit alpha transducin 3provided by MGI
    Primary source
    MGI:MGI:3588268
    See related
    Ensembl:ENSMUSG00000028777 AllianceGenome:MGI:3588268
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gtn; Hg1e; Ggust
    Summary
    Enables GTPase activity. Acts upstream of or within G protein-coupled receptor signaling pathway and sensory perception of taste. Located in cytoplasm. Part of heterotrimeric G-protein complex. Is expressed in alimentary system and liver. Orthologous to human GNAT3 (G protein subunit alpha transducin 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Gnat3 in Genome Data Viewer
    Location:
    5 A3; 5 8.14 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (18167568..18224666)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (17962570..18019668)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr5:17322004-17322304 Neighboring gene STARR-positive B cell enhancer ABC_E6307 Neighboring gene STARR-positive B cell enhancer ABC_E8043 Neighboring gene CD36 molecule Neighboring gene STARR-positive B cell enhancer ABC_E9632 Neighboring gene STARR-seq mESC enhancer starr_12500 Neighboring gene predicted gene, 31612 Neighboring gene STARR-positive B cell enhancer mm9_chr5:17515822-17516123 Neighboring gene STARR-positive B cell enhancer ABC_E2153 Neighboring gene STARR-seq mESC enhancer starr_12501 Neighboring gene predicted gene, 54321 Neighboring gene STARR-seq mESC enhancer starr_12503 Neighboring gene STARR-seq mESC enhancer starr_12504 Neighboring gene STARR-seq mESC enhancer starr_12507 Neighboring gene STARR-seq mESC enhancer starr_12508 Neighboring gene STARR-seq mESC enhancer starr_12509 Neighboring gene STARR-seq mESC enhancer starr_12510 Neighboring gene G protein subunit alpha i1 Neighboring gene STARR-seq mESC enhancer starr_12511 Neighboring gene predicted gene 3527 Neighboring gene STARR-seq mESC enhancer starr_12512 Neighboring gene predicted gene, 31752

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G-protein beta/gamma-subunit complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G-protein beta/gamma-subunit complex binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in acrosomal vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in acrosomal vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in axoneme IEA
    Inferred from Electronic Annotation
    more info
     
    located_in axoneme ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of heterotrimeric G-protein complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    guanine nucleotide-binding protein G(t) subunit alpha-3
    Names
    alpha-gustducin
    guanine nucleotide binding protein, alpha transducing 3
    gustducin alpha-3 chain
    heterotrimeric guanine nucleotide-binding protein 1e
    NP_001074612.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081143.1NP_001074612.1  guanine nucleotide-binding protein G(t) subunit alpha-3

      See identical proteins and their annotated locations for NP_001074612.1

      Status: PROVISIONAL

      Source sequence(s)
      AC129572
      Consensus CDS
      CCDS39017.1
      UniProtKB/Swiss-Prot
      Q3V3I2
      UniProtKB/TrEMBL
      B2RVZ3
      Related
      ENSMUSP00000030561.8, ENSMUST00000030561.9
      Conserved Domains (1) summary
      cd00066
      Location:34348
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      18167568..18224666
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)