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    Igk-V4 immunoglobulin kappa chain variable 4 (V4) [ Mus musculus (house mouse) ]

    Gene ID: 16121, updated on 17-Aug-2024

    Summary

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    Official Symbol
    Igk-V4provided by MGI
    Official Full Name
    immunoglobulin kappa chain variable 4 (V4)provided by MGI
    Primary source
    MGI:MGI:96516
    Gene type
    other
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700129E19Rik
    Annotation information
    not in current annotation release
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    Genomic context

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    Location:
    chromosome: 6

    Bibliography

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    Related articles in PubMed

    1. Light chain germ-line genes and the immune response to 2-phenyloxazolone. Even J, et al. EMBO J, 1985 Dec 16. PMID 3937727, Free PMC Article
    2. The 5' boundary of somatic hypermutation in a V kappa gene is in the leader intron. Rada C, et al. Eur J Immunol, 1994 Jun. PMID 8206104
    3. Intron sequences determine the expression of kappa light chain genes. Chou CL, et al. Mol Immunol, 1994 Feb. PMID 8309481
    4. Two kappa immunoglobulin genes are expressed in the myeloma S107. Kwan SP, et al. Cell, 1981 Oct. PMID 6799208
    5. An insertion-deletion event in murine immunoglobulin kappa gene resembles mutations at heavy-chain disease loci. Chou CL, et al. Somat Cell Mol Genet, 1993 Mar. PMID 8511672

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. V(kappa)4-J(kappa)4 targeted mice exhibited an intermediate phenotype with respect to these two mechanisms of B cell tolerance.
      Title: The efficiency of B cell receptor (BCR) editing is dependent on BCR light chain rearrangement status.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Nucleotide Protein Strain
    Heading Accession and Version

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