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    Rnase11 ribonuclease, RNase A family, 11 (non-active) [ Mus musculus (house mouse) ]

    Gene ID: 497113, updated on 27-Dec-2024

    Summary

    Official Symbol
    Rnase11provided by MGI
    Official Full Name
    ribonuclease, RNase A family, 11 (non-active)provided by MGI
    Primary source
    MGI:MGI:3528583
    See related
    Ensembl:ENSMUSG00000059648 AllianceGenome:MGI:3528583
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Raj1
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be involved in defense response to Gram-positive bacterium. Predicted to be located in extracellular region. Orthologous to human RNASE11 (ribonuclease A family member 11 (inactive)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward genital fat pad adult (RPKM 8.1) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rnase11 in Genome Data Viewer
    Location:
    14 C1; 14 26.36 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (51286150..51293159, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (51048693..51055702, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ribonuclease, RNase A family, 10 (non-active) Neighboring gene STARR-seq mESC enhancer starr_36664 Neighboring gene STARR-positive B cell enhancer mm9_chr14:51646418-51646719 Neighboring gene ribonuclease, RNase A family, 9 (non-active) Neighboring gene STARR-seq mESC enhancer starr_36665 Neighboring gene ribonuclease, RNase A family, 12 (non-active) Neighboring gene predicted gene, 52088

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    NOT enables RNA nuclease activity IKR
    Inferred from Key Residues
    more info
    PubMed 
    enables molecular_function ND
    No biological Data available
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in defense response to Gram-positive bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    putative inactive ribonuclease 11
    Names
    ribonuclease A j1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011877.2NP_001011877.1  putative inactive ribonuclease 11 precursor

      See identical proteins and their annotated locations for NP_001011877.1

      Status: VALIDATED

      Source sequence(s)
      AC136376
      Consensus CDS
      CCDS27031.1
      UniProtKB/Swiss-Prot
      B9EJ01, Q5GAM9
      UniProtKB/TrEMBL
      W0UVF9
      Related
      ENSMUSP00000075472.4, ENSMUST00000076106.4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      51286150..51293159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519222.3XP_006519285.2  putative inactive ribonuclease 11 isoform X1

    2. XM_011245112.2XP_011243414.1  putative inactive ribonuclease 11 isoform X2

      See identical proteins and their annotated locations for XP_011243414.1

      UniProtKB/Swiss-Prot
      B9EJ01, Q5GAM9
      UniProtKB/TrEMBL
      W0UVF9
    3. XM_006519220.2XP_006519283.1  putative inactive ribonuclease 11 isoform X2

      See identical proteins and their annotated locations for XP_006519283.1

      UniProtKB/Swiss-Prot
      B9EJ01, Q5GAM9
      UniProtKB/TrEMBL
      W0UVF9