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    SIA1 Sia1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854305, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SIA1
    Official Full Name
    Sia1p
    Primary source
    SGD:S000005663
    Locus tag
    YOR137C
    See related
    AllianceGenome:SGD:S000005663; FungiDB:YOR137C; VEuPathDB:YOR137C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable phosphoprotein phosphatase activity. Involved in proton transmembrane transport. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SIA1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (581813..583681, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene GTPase-activating protein BAG7 Neighboring gene isocitrate dehydrogenase (NAD(+)) IDH2 Neighboring gene Rup1p Neighboring gene Sfl1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Yeast gene YOR137c is involved in the activation of the yeast plasma membrane H+-ATPase by glucose. de la Fuente N, et al. FEBS Lett, 1997 Dec 22. PMID 9450541
    2. Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Valentini SR, et al. Genetics, 2002 Feb. PMID 11861547, Free PMC Article
    3. Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation. Chiolo I, et al. Mol Cell Biol, 2005 Jul. PMID 15964827, Free PMC Article
    4. Analysis of the TORC1 interactome reveals a spatially distinct function of TORC1 in mRNP complexes. Chang Y, et al. J Cell Biol, 2021 Apr 5. PMID 33566094, Free PMC Article
    5. Whi3, a developmental regulator of budding yeast, binds a large set of mRNAs functionally related to the endoplasmic reticulum. Colomina N, et al. J Biol Chem, 2008 Oct 17. PMID 18667435, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables phosphoprotein phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proton transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Sia1p
    NP_014780.3
    • Protein of unassigned function; involved in activation of the Pma1p plasma membrane H+-ATPase by glucose; contains peptide signal for membrane localization

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      581813..583681 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183556.3 → NP_014780.3  TPA: Sia1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014780.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2J4, Q12212
      UniProtKB/TrEMBL
      A6ZNY3, B3LJH7, B5VS25, C7GN85, C8ZI99, G2WN11
      Conserved Domains (1) summary
      cl13995
      Location:309 → 575
      MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12212.1

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