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    Scgb2b20 secretoglobin, family 2B, member 20 [ Mus musculus (house mouse) ]

    Gene ID: 494519, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Scgb2b20provided by MGI
    Official Full Name
    secretoglobin, family 2B, member 20provided by MGI
    Primary source
    MGI:MGI:3514009
    See related
    Ensembl:ENSMUSG00000094305 AllianceGenome:MGI:3514009
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C2c; Abpd; Abpbg20; Scgb2b2
    Summary
    Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Scgb2b20 in Genome Data Viewer
    Location:
    7 B1; 7 19.35 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (33063768..33065744, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (33364343..33366319, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene secretoglobin, family 1B, member 19 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_18564 Neighboring gene secretoglobin, family 1B, member 20 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Lacrimal androgen-binding proteins protect against Aspergillus fumigatus keratitis in mice. Lyu L, et al. Int Immunopharmacol, 2020 Nov. PMID 32916626
    2. Secretoglobins: sexually dimorphic expression of androgen-binding protein mRNA in mouse lacrimal glands. Remington SG, et al. Invest Ophthalmol Vis Sci, 2005 Jan. PMID 15623751
    3. Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. Reynolds SD, et al. Am J Respir Crit Care Med, 2002 Dec 1. PMID 12406855
    4. Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily. Jackson BC, et al. Hum Genomics, 2011 Oct. PMID 22155607, Free PMC Article
    5. Rapid bursts of androgen-binding protein (Abp) gene duplication occurred independently in diverse mammals. Laukaitis CM, et al. BMC Evol Biol, 2008 Feb 12. PMID 18269759, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Lacrimal androgen-binding proteins protect against Aspergillus fumigatus keratitis in mice.
      Title: Lacrimal androgen-binding proteins protect against Aspergillus fumigatus keratitis in mice.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    secretoglobin family 2B member 20
    Names
    allergen dI chain C2C
    androgen binding protein delta
    lacrimal androgen-binding protein delta
    secretoglobin, family 2B, member 2

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009952.2 → NP_001009952.2  secretoglobin family 2B member 20 precursor

      See identical proteins and their annotated locations for NP_001009952.2

      Status: VALIDATED

      Source sequence(s)
      CK616187, CK616386
      Consensus CDS
      CCDS21131.1
      UniProtKB/Swiss-Prot
      Q7M746, Q9JI02
      UniProtKB/TrEMBL
      J3QK77
      Related
      ENSMUSP00000137484.2, ENSMUST00000179248.2
      Conserved Domains (1) summary
      pfam09252
      Location:24 → 90
      Feld-I_B; Allergen Fel d I-B chain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      33063768..33065744 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153231.1 → XP_036009124.1  secretoglobin family 2B member 20 isoform X2

      Conserved Domains (1) summary
      pfam09252
      Location:23 → 73
      Feld-I_B; Allergen Fel d I-B chain

    2. XM_006540168.3 → XP_006540231.1  secretoglobin family 2B member 20 isoform X1

      Conserved Domains (1) summary
      pfam09252
      Location:24 → 74
      Feld-I_B; Allergen Fel d I-B chain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9JI02.1 GenPept UniProtKB/Swiss-Prot:Q9JI02

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