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    MPA43 Mpa43p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855472, updated on 9-Dec-2024

    Summary

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    Official Symbol
    MPA43
    Official Full Name
    Mpa43p
    Primary source
    SGD:S000005193
    Locus tag
    YNL249C
    See related
    AllianceGenome:SGD:S000005193; FungiDB:YNL249C; VEuPathDB:YNL249C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable D-ribulokinase activity. Predicted to be involved in pentose metabolic process. Located in mitochondrion. Orthologous to human FGGY (FGGY carbohydrate kinase domain containing). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MPA43 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (179394..181022, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Nrd1 complex RNA-binding subunit Neighboring gene MRX complex DNA-binding subunit Neighboring gene DNA-directed RNA polymerase I subunit RPA49 Neighboring gene cysteine--tRNA ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular Identification of d-Ribulokinase in Budding Yeast and Mammals. Singh C, et al. J Biol Chem, 2017 Jan 20. PMID 27909055, Free PMC Article
    2. Long 3'-UTRs target wild-type mRNAs for nonsense-mediated mRNA decay in Saccharomyces cerevisiae. Kebaara BW, et al. Nucleic Acids Res, 2009 May. PMID 19270062, Free PMC Article
    3. Sequence analysis of the 33 kb long region between ORC5 and SUI1 from the left arm of chromosome XIV from Saccharomyces cerevisiae. Sen-Gupta M, et al. Yeast, 1997 Jul. PMID 9234673
    4. An amphibian-derived, cationic, alpha-helical antimicrobial peptide kills yeast by caspase-independent but AIF-dependent programmed cell death. Morton CO, et al. Mol Microbiol, 2007 Jul. PMID 17587229
    5. Selective defects in gene expression control genome instability in yeast splicing mutants. Tam AS, et al. Mol Biol Cell, 2019 Jan 15. PMID 30462576, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables D-ribulokinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carbohydrate phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pentose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Mpa43p
    NP_014150.1
    • hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      179394..181022 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183087.1 → NP_014150.1  TPA: Mpa43p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014150.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0U4, P53583
      UniProtKB/TrEMBL
      B3LP93, B5VQG0, C8ZFY8, G2WLL7, N1NWZ1
      Conserved Domains (1) summary
      COG1069
      Location:4 → 542
      AraB; Ribulose kinase [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53583.1

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