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    Cenpn centromere protein N [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361416, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cenpnprovided by RGD
    Official Full Name
    centromere protein Nprovided by RGD
    Primary source
    RGD:1310953
    See related
    EnsemblRapid:ENSRNOG00000011296 AllianceGenome:RGD:1310953
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Da2-4; Da2-27; RGD1310953
    Summary
    Predicted to be involved in CENP-A containing chromatin assembly and chromosome segregation. Predicted to be located in chromosome, centromeric region and nucleus. Predicted to be part of inner kinetochore. Predicted to be active in nucleoplasm. Orthologous to human CENPN (centromere protein N). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 98.0), Thymus (RPKM 68.3) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cenpn in Genome Data Viewer
    Location:
    19q12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (61880101..61902850)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (44971265..44994019)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (49457461..49479989)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene dynein light chain roadblock-type 2 Neighboring gene chromodomain Y-like 2 Neighboring gene uncharacterized LOC134483651 Neighboring gene C-x(9)-C motif containing 2 Neighboring gene similar to human chromosome 16 open reading frame 46 Neighboring gene ATM interactor

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC94524

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in CENP-A containing chromatin assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    part_of inner kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    centromere protein N
    Names
    CENP-N

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008366.1NP_001008367.1  centromere protein N

      See identical proteins and their annotated locations for NP_001008367.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085839
      UniProtKB/Swiss-Prot
      Q5U2W4
      UniProtKB/TrEMBL
      A0A0H2UHI9, A6IZF9
      Conserved Domains (1) summary
      pfam05238
      Location:4340
      CENP-N; Kinetochore protein CHL4 like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      61880101..61902850
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039097868.2XP_038953796.1  centromere protein N isoform X1

      UniProtKB/Swiss-Prot
      Q5U2W4
      UniProtKB/TrEMBL
      A0A0H2UHI9, A6IZF9
      Related
      ENSRNOP00000015158.6, ENSRNOT00000015158.8
      Conserved Domains (1) summary
      pfam05238
      Location:4340
      CENP-N; Kinetochore protein CHL4 like
    2. XM_063278143.1XP_063134213.1  centromere protein N isoform X2

      UniProtKB/TrEMBL
      A0A0H2UHI9, A0A8L2UQ64
      Related
      ENSRNOP00000071328.3, ENSRNOT00000084445.3
    3. XM_006255687.5XP_006255749.1  centromere protein N isoform X1

      See identical proteins and their annotated locations for XP_006255749.1

      UniProtKB/Swiss-Prot
      Q5U2W4
      UniProtKB/TrEMBL
      A0A0H2UHI9, A6IZF9
      Conserved Domains (1) summary
      pfam05238
      Location:4340
      CENP-N; Kinetochore protein CHL4 like
    4. XM_039097869.2XP_038953797.1  centromere protein N isoform X1

      UniProtKB/Swiss-Prot
      Q5U2W4
      UniProtKB/TrEMBL
      A0A0H2UHI9, A6IZF9
      Conserved Domains (1) summary
      pfam05238
      Location:4340
      CENP-N; Kinetochore protein CHL4 like
    5. XM_006255692.5XP_006255754.1  centromere protein N isoform X2

      See identical proteins and their annotated locations for XP_006255754.1

      UniProtKB/TrEMBL
      A0A0H2UHI9, A0A8L2UQ64
      Conserved Domains (1) summary
      pfam05238
      Location:3320
      CENP-N; Kinetochore protein CHL4 like
    6. XM_006255689.5XP_006255751.1  centromere protein N isoform X1

      See identical proteins and their annotated locations for XP_006255751.1

      UniProtKB/Swiss-Prot
      Q5U2W4
      UniProtKB/TrEMBL
      A0A0H2UHI9, A6IZF9
      Conserved Domains (1) summary
      pfam05238
      Location:4340
      CENP-N; Kinetochore protein CHL4 like
    7. XM_006255686.5XP_006255748.1  centromere protein N isoform X1

      See identical proteins and their annotated locations for XP_006255748.1

      UniProtKB/Swiss-Prot
      Q5U2W4
      UniProtKB/TrEMBL
      A0A0H2UHI9, A6IZF9
      Conserved Domains (1) summary
      pfam05238
      Location:4340
      CENP-N; Kinetochore protein CHL4 like
    8. XM_006255691.5XP_006255753.1  centromere protein N isoform X2

      See identical proteins and their annotated locations for XP_006255753.1

      UniProtKB/TrEMBL
      A0A0H2UHI9, A0A8L2UQ64
      Conserved Domains (1) summary
      pfam05238
      Location:3320
      CENP-N; Kinetochore protein CHL4 like
    9. XM_039097870.2XP_038953798.1  centromere protein N isoform X1

      UniProtKB/Swiss-Prot
      Q5U2W4
      UniProtKB/TrEMBL
      A0A0H2UHI9, A6IZF9
      Conserved Domains (1) summary
      pfam05238
      Location:4340
      CENP-N; Kinetochore protein CHL4 like