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    LOG1 Log1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853391, updated on 9-Dec-2024

    Summary

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    Official Symbol
    LOG1
    Official Full Name
    Log1p
    Primary source
    SGD:S000003591
    Locus tag
    YJL055W
    See related
    AllianceGenome:SGD:S000003591; FungiDB:YJL055W; VEuPathDB:YJL055W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable cytokinin riboside 5'-monophosphate phosphoribohydrolase activity. Involved in response to purine-containing compound. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See LOG1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (333357..334094)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene protein kinase IKS1 Neighboring gene Zap1p Neighboring gene Tim54p Neighboring gene retromer subunit PEP8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Control of 5-FOA and 5-FU resistance by Saccharomyces cerevisiae YJL055W. Ko N, et al. Yeast, 2008 Feb. PMID 18186026
    2. Gene dosage effects in yeast support broader roles for the LOG1, HAM1 and DUT1 genes in detoxification of nucleotide analogues. Carlsson M, et al. PLoS One, 2018. PMID 29738539, Free PMC Article
    3. A Ham1p-dependent mechanism and modulation of the pyrimidine biosynthetic pathway can both confer resistance to 5-fluorouracil in yeast. Carlsson M, et al. PLoS One, 2013. PMID 24124444, Free PMC Article
    4. Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast. Stepchenkova EI, et al. BMC Genet, 2005 Jun 2. PMID 15932646, Free PMC Article
    5. The S. cerevisiae m6A-reader Pho92 promotes timely meiotic recombination by controlling key methylated transcripts. Scutenaire J, et al. Nucleic Acids Res, 2023 Jan 25. PMID 35934316, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables cytokinin riboside 5'-monophosphate phosphoribohydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytokinin biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytokinin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to purine-containing compound IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Log1p
    NP_012480.1
    • hypothetical protein; functions together with HAM1 to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA, without affecting uptake or incorporation of uracil into RNA; proposed to be involved in the metabolism of purine and pyrimidine base analogues; deletion mutants are sensitive to HAP and AHA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      333357..334094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181488.1 → NP_012480.1  TPA: Log1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012480.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWC7, P47044
      UniProtKB/TrEMBL
      A6ZPR9, B3LQ55, C7GR57, C8ZBF9, G2WGW1
      Conserved Domains (1) summary
      TIGR00730
      Location:19 → 222
      TIGR00730; TIGR00730 family protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47044.1

    Gene LinkOut

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