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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853276, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000003699
    Locus tag
    YJL163C
    See related
    AllianceGenome:SGD:S000003699; FungiDB:YJL163C; VEuPathDB:YJL163C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in fungal-type vacuole membrane. Human ortholog(s) of this gene implicated in hereditary folate malabsorption. Orthologous to several human genes including SLC46A1 (solute carrier family 46 member 1) and SLC46A3 (solute carrier family 46 member 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (111666..113333, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene protein kinase HAL5 Neighboring gene cAMP-dependent protein kinase catalytic subunit TPK1 Neighboring gene Jjj2p Neighboring gene tRNA-Glu

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cross-linking Mass Spectrometry Analysis of the Yeast Nucleus Reveals Extensive Protein-Protein Interactions Not Detected by Systematic Two-Hybrid or Affinity Purification-Mass Spectrometry. Bartolec TK, et al. Anal Chem, 2020 Jan 21. PMID 31851481
    2. Whi3, a developmental regulator of budding yeast, binds a large set of mRNAs functionally related to the endoplasmic reticulum. Colomina N, et al. J Biol Chem, 2008 Oct 17. PMID 18667435, Free PMC Article
    3. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. Galibert F, et al. EMBO J, 1996 May 1. PMID 8641269, Free PMC Article
    4. A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export. Oliete-Calvo P, et al. EMBO Rep, 2018 Nov. PMID 30249596, Free PMC Article
    5. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in fungal-type vacuole membrane HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      111666..113333 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181596.1 → NP_012372.1  TPA: uncharacterized protein YJL163C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012372.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW24, P46996
      UniProtKB/TrEMBL
      A6ZQG9, C8ZB56, N1P1Y0
      Conserved Domains (1) summary
      cl28910
      Location:139 → 545
      MFS; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P46996.1

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