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    RSM22 tRNA methyltransferase RSM22 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853701, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RSM22
    Official Full Name
    tRNA methyltransferase RSM22
    Primary source
    SGD:S000001638
    Locus tag
    YKL155C
    See related
    AllianceGenome:SGD:S000001638; FungiDB:YKL155C; VEuPathDB:YKL155C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial small ribosomal subunit. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RSM22 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (159456..161342, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene metallo-aminopeptidase Neighboring gene ribosomal 40S subunit protein S27A Neighboring gene Signal recognition particle receptor subunit beta Neighboring gene tRNA-Arg

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae. Alam J, et al. Acta Crystallogr D Struct Biol, 2021 Jun 1. PMID 34076597, Free PMC Article
    2. Deletion of a subgroup of ribosome-related genes minimizes hypoxia-induced changes and confers hypoxia tolerance. Shah AN, et al. Physiol Genomics, 2011 Jul 27. PMID 21586670, Free PMC Article
    3. ATG18 and FAB1 are involved in dehydration stress tolerance in Saccharomyces cerevisiae. López-Martínez G, et al. PLoS One, 2015. PMID 25803831, Free PMC Article
    4. Probabilistic approach to predicting substrate specificity of methyltransferases. Szczepińska T, et al. PLoS Comput Biol, 2014 Mar. PMID 24651469, Free PMC Article
    5. Multiple Motif Scanning to identify methyltransferases from the yeast proteome. Petrossian TC, et al. Mol Cell Proteomics, 2009 Jul. PMID 19351663, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tRNA methyltransferase RSM22
    NP_012767.1
    • Mitochondrial ribosomal protein of the small subunit; also predicted to be an S-adenosylmethionine-dependent RNA methyltransferase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      159456..161342 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179721.1 → NP_012767.1  TPA: tRNA methyltransferase RSM22 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012767.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VX43, P36056
      UniProtKB/TrEMBL
      A6ZZG8, B3LQU7, B5VM09, C7GT78, C8ZC20, N1P0P5
      Conserved Domains (1) summary
      COG5459
      Location:43 → 628
      Rsm22; Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36056.1

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