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    sha shavenoid [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36213, updated on 9-Dec-2024

    Summary

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    Official Symbol
    shaprovided by FlyBase
    Official Full Name
    shavenoidprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003382
    Locus tag
    Dmel_CG13209
    See related
    AllianceGenome:FB:FBgn0003382
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13209; Dmel\CG13209; koj; lincRNA.286; Sha
    Summary
    Involved in antennal morphogenesis; cuticle pattern formation; and imaginal disc-derived wing hair organization. Located in cell cortex. Is expressed in embryonic dorsal epidermis; embryonic ventral epidermis; and mesothoracic leg. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See sha in Genome Data Viewer
    Location:
    47F1-47F3; 2-64 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11324314..11336463)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7211819..7223968)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene no mechanoreceptor potential A Neighboring gene Odorant receptor 47b Neighboring gene lambdaTry Neighboring gene kappaTry

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Early role of the esc+ gene product in the determination of segments in Drosophila. Struhl G, et al. Cell, 1982 Nov. PMID 7159925
    2. Evolution of mir-92a underlies natural morphological variation in Drosophila melanogaster. Arif S, et al. Curr Biol, 2013 Mar 18. PMID 23453955, Free PMC Article
    3. A cytoskeletal activator and inhibitor are downstream targets of the frizzled/starry night planar cell polarity pathway in the Drosophila epidermis. Adler PN. Prog Biophys Mol Biol, 2018 Sep. PMID 29649492
    4. A novel genetic tool for clonal analysis of fourth chromosome mutations. Sousa-Neves R, et al. Fly (Austin), 2012 Jan-Mar. PMID 22198523, Free PMC Article
    5. Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity. Struhl G, et al. Development, 2012 Oct. PMID 22949620, Free PMC Article

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. sha (also known as kojak) is necessary but not sufficient to activate the cytoskeleton to drive wing hair formation.
      Title: The shavenoid gene of Drosophila encodes a novel actin cytoskeleton interacting protein that promotes wing hair morphogenesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in antennal morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cuticle pattern formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in cuticle pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in epidermal cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in imaginal disc-derived wing hair organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in imaginal disc-derived wing hair organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    shavenoid
    Names
    CG13209-PA
    CG13209-PB
    CG13209-PC
    kojak
    sha-PA
    sha-PB
    sha-PC
    shavenoid/kojak

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11324314..11336463
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144173.3 → NP_001137645.1  shavenoid, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137645.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7YZF2

    2. NM_136828.3 → NP_610672.1  shavenoid, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610672.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8J5
      Related
      FBpp0087221

    3. NM_001273960.1 → NP_001260889.1  shavenoid, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260889.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEL5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KEL5 A0A0B4KEL5
    A1Z8J5 A1Z8J5
    B7YZF2 B7YZF2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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