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    TM9SF3 Transmembrane 9 superfamily protein member 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38635, updated on 9-Dec-2024

    Summary

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    Official Symbol
    TM9SF3provided by FlyBase
    Official Full Name
    Transmembrane 9 superfamily protein member 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0035622
    Locus tag
    Dmel_CG10590
    See related
    AllianceGenome:FB:FBgn0035622
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10590; Dmel\CG10590
    Summary
    Predicted to be involved in protein localization to membrane. Predicted to be active in membrane. Is expressed in adult head; embryonic/larval salivary gland; and organism. Orthologous to human TM9SF3 (transmembrane 9 superfamily member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See TM9SF3 in Genome Data Viewer
    Location:
    64D5-64D6; 3-14 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (5601096..5603979, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (5594196..5597079, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Alkaline phosphatase 9 Neighboring gene uncharacterized protein Neighboring gene methuselah-like 2 Neighboring gene Esa1-associated factor 6 Neighboring gene Blimp-1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The nonaspanins TM9SF2 and TM9SF4 regulate the plasma membrane localization and signalling activity of the peptidoglycan recognition protein PGRP-LC in Drosophila. Perrin J, et al. J Innate Immun, 2015. PMID 25139117, Free PMC Article
    2. Comparative analysis of nonaspanin protein sequences and expression studies in zebrafish. Pruvot B, et al. Immunogenetics, 2010 Oct. PMID 20820770
    3. TM9SF4 is required for Drosophila cellular immunity via cell adhesion and phagocytosis. Bergeret E, et al. J Cell Sci, 2008 Oct 15. PMID 18796536
    4. Genome-wide analysis in Drosophila reveals diet-by-gene interactions and uncovers diet-responsive genes. Francis D, et al. G3 (Bethesda), 2021 Sep 27. PMID 34568906, Free PMC Article
    5. Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates. Olson JM, et al. G3 (Bethesda), 2019 Nov 5. PMID 31690598, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in protein localization to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane 9 superfamily protein member 3
    Names
    CG10590-PA
    TM9SF3-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      5601096..5603979 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139722.4 → NP_647979.1  transmembrane 9 superfamily protein member 3 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647979.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYP6, Q9VRN1
      Related
      FBpp0076833
      Conserved Domains (1) summary
      pfam02990
      Location:60 → 530
      EMP70; Endomembrane protein 70
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRN1 Q9VRN1

    Gene LinkOut

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