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    CG3703 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31045, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3703provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040348
    Locus tag
    Dmel_CG3703
    See related
    AllianceGenome:FB:FBgn0040348
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BACR7A4.15; Dmel\CG3703; EG:BACR7A4.15
    Summary
    Predicted to enable GTPase activator activity. Predicted to be involved in intracellular protein transport. Predicted to be active in cytoplasm. Is expressed in embryonic brain; embryonic head sensory system; and larval ventral nerve cord. Orthologous to human RUNDC1 (RUN domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3703 in Genome Data Viewer
    Location:
    1D2-1D2; 1-0 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (942474..945773, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (836507..839806, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene TRAM Neighboring gene uncharacterized protein Neighboring gene mus81 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Template disruptions and failure of double Holliday junction dissolution during double-strand break repair in Drosophila BLM mutants. Johnson-Schlitz D, et al. Proc Natl Acad Sci U S A, 2006 Nov 7. PMID 17075047, Free PMC Article
    2. The endogenous siRNA pathway in Drosophila impacts stress resistance and lifespan by regulating metabolic homeostasis. Lim DH, et al. FEBS Lett, 2011 Oct 3. PMID 21889502
    3. Rab2 drives axonal transport of dense core vesicles and lysosomal organelles. Lund VK, et al. Cell Rep, 2021 Apr 13. PMID 33852866
    4. Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. Page AR, et al. EMBO J, 2005 Dec 21. PMID 16369566, Free PMC Article
    5. Identification of neural outgrowth genes using genome-wide RNAi. Sepp KJ, et al. PLoS Genet, 2008 Jul 4. PMID 18604272, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3703-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      942474..945773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130518.3 → NP_569874.1  uncharacterized protein Dmel_CG3703 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569874.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NF74, Q9W5C1
      Related
      FBpp0070180
      Conserved Domains (1) summary
      pfam02759
      Location:516 → 703
      RUN; RUN domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NF74 Q9NF74
    Q9W5C1 Q9W5C1

    Gene LinkOut

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