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    CG8475 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34114, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8475provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031995
    Locus tag
    Dmel_CG8475
    See related
    AllianceGenome:FB:FBgn0031995
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8475
    Summary
    Predicted to enable calmodulin binding activity. Predicted to be involved in positive regulation of glycogen catabolic process. Predicted to be part of phosphorylase kinase complex. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in glycogen storage disease IXb. Orthologous to human PHKB (phosphorylase kinase regulatory subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8475 in Genome Data Viewer
    Location:
    28F1-28F1; 2-30 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8190808..8196918, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8190808..8196918, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene piezo Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44116 Neighboring gene uncharacterized protein Neighboring gene Post-GPI attachment to proteins 5 Neighboring gene Sodium/solute co-transporter-like 5A11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mass Spectrometry-Based Screening Platform Reveals Orco Interactome in Drosophila melanogaster. Yu KE, et al. Mol Cells, 2018 Feb 28. PMID 29429152, Free PMC Article
    2. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
    3. Affinity Density: a novel genomic approach to the identification of transcription factor regulatory targets. Hazelett DJ, et al. Bioinformatics, 2009 Jul 1. PMID 19401399, Free PMC Article
    4. Prediction and verification of microRNA targets by MovingTargets, a highly adaptable prediction method. Burgler C, et al. BMC Genomics, 2005 Jun 8. PMID 15943864, Free PMC Article
    5. Discovery and Visualization of Age-Dependent Patterns in the Diurnal Transcriptome of Drosophila. Sebastian B, et al. J Circadian Rhythms, 2022. PMID 36561348, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in glycogen metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of glycogen catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of phosphorylase kinase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8475-PA
    CG8475-PB
    CG8475-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8190808..8196918 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273301.1 → NP_001260230.1  uncharacterized protein Dmel_CG8475, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260230.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCI5
      Conserved Domains (1) summary
      pfam00723
      Location:49 → 468
      Glyco_hydro_15; Glycosyl hydrolases family 15

    2. NM_135345.3 → NP_609189.2  uncharacterized protein Dmel_CG8475, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609189.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F9VMG4, Q8IPG3, Q8SXP4, Q9VLS1
      Related
      FBpp0079254
      Conserved Domains (1) summary
      pfam00723
      Location:49 → 468
      Glyco_hydro_15; Glycosyl hydrolases family 15

    3. NM_164797.3 → NP_723356.1  uncharacterized protein Dmel_CG8475, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723356.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VLS1
      Related
      FBpp0079255
      Conserved Domains (1) summary
      pfam00723
      Location:49 → 468
      Glyco_hydro_15; Glycosyl hydrolases family 15
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PCI5 M9PCI5
    Q9VLS1.2 Q9VLS1

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