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    CG18418 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38572, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG18418provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035568
    Locus tag
    Dmel_CG18418
    See related
    AllianceGenome:FB:FBgn0035568
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.190; Dmel\CG18418
    Summary
    Predicted to enable C4-dicarboxylate transmembrane transporter activity; antiporter activity; and sulfur compound transmembrane transporter activity. Predicted to be involved in C4-dicarboxylate transport; inorganic anion transmembrane transport; and thiosulfate transport. Is expressed in adult head. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SLC25A11 (solute carrier family 25 member 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG18418 in Genome Data Viewer
    Location:
    64B13-64B13; 3-12 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (4688929..4690070, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (4688929..4690070, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene axotactin Neighboring gene uncharacterized protein Neighboring gene Rho guanine nucleotide exchange factor at 64C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic Signatures of Drug Response Variability in Drosophila melanogaster. Rohde PD, et al. Genetics, 2019 Oct. PMID 31455722, Free PMC Article
    2. Widespread adaptive evolution of Drosophila genes with sex-biased expression. Pröschel M, et al. Genetics, 2006 Oct. PMID 16951084, Free PMC Article
    3. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. Magwire MM, et al. PLoS Genet, 2010 Jul 29. PMID 20686706, Free PMC Article
    4. Aralar Sequesters GABA into Hyperactive Mitochondria, Causing Social Behavior Deficits. Kanellopoulos AK, et al. Cell, 2020 Mar 19. PMID 32200800
    5. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18418-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      4688929..4690070 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139667.2 → NP_647924.2  uncharacterized protein Dmel_CG18418 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647924.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0AMJ5, A0AMJ8, A0AMK3, C0MI48, Q8SXB4, Q9VZ93
      Related
      FBpp0073222, FBtr0073366
      Conserved Domains (2) summary
      PTZ00169
      Location:18 → 296
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:10 → 108
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SXB4 Q8SXB4
    Q9VZ93 Q9VZ93

    Gene LinkOut

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