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    CG42750 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35090, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG42750provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0261804
    Locus tag
    Dmel_CG42750
    See related
    AllianceGenome:FB:FBgn0261804
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15157; CG15158; CG31746; CG31786; CG42400; CG7167; CG7198; Dmel\CG42750
    Old locus tag
    Dmel_CG15157; Dmel_CG31746; Dmel_CG31786; Dmel_CG42400
    Summary
    Predicted to enable metallodipeptidase activity. Predicted to be involved in proteolysis. Is expressed in adult head. Orthologous to several human genes including DPEP2 (dipeptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG42750 in Genome Data Viewer
    Location:
    36E6-36F2; 2-53 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18159811..18275770, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18159811..18275770, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Jumonji domain containing 4 Neighboring gene long non-coding RNA:CR44900 Neighboring gene Protein tyrosine phosphatase 36E Neighboring gene antisense RNA:CR43413 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43406 Neighboring gene long non-coding RNA:CR43408 Neighboring gene long non-coding RNA:CR44901 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44902 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Context-dependent genetic architecture of Drosophila life span. Huang W, et al. PLoS Biol, 2020 Mar. PMID 32134916, Free PMC Article
    2. A genome-wide analysis of courting and mating responses in Drosophila melanogaster females. Lawniczak MK, et al. Genome, 2004 Oct. PMID 15499404
    3. Identification of genes that influence gurken expression. Geng C, et al. Fly (Austin), 2007 Sep-Oct. PMID 18836312
    4. Genome-wide identification of in vivo Drosophila Engrailed-binding DNA fragments and related target genes. Solano PJ, et al. Development, 2003 Apr. PMID 12588842
    5. Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics. Croset V, et al. Elife, 2018 Apr 19. PMID 29671739, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    mobile_element

    • Loc: c18177267-18177178 mobile_element_type = transposon:INE-1{}3503

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metallodipeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG42750-PB
    CG42750-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18159811..18275770 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299103.1 → NP_001286032.1  uncharacterized protein Dmel_CG42750, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286032.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JA84
      Conserved Domains (1) summary
      pfam01244
      Location:700 → 1034
      Peptidase_M19; Membrane dipeptidase (Peptidase family M19)

    2. NM_165245.4 → NP_724101.4  uncharacterized protein Dmel_CG42750, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724101.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJ94
      Conserved Domains (1) summary
      pfam01244
      Location:701 → 1035
      Peptidase_M19; Membrane dipeptidase (Peptidase family M19)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VJ94 Q9VJ94
    X2JA84 X2JA84

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