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    CG6220 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36520, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6220provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033865
    Locus tag
    Dmel_CG6220
    See related
    AllianceGenome:FB:FBgn0033865
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6220
    Summary
    Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Cdc73/Paf1 complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6220 in Genome Data Viewer
    Location:
    50C2-50C2; 2-68 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13691707..13693369, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9579212..9580874, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene teiresias Neighboring gene long non-coding RNA:CR45031 Neighboring gene long non-coding RNA:CR45032 Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 50Ca Neighboring gene Sperm-Leucylaminopeptidase 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo. Mosimann C, et al. Cell, 2006 Apr 21. PMID 16630820
    2. Nociceptor-Enriched Genes Required for Normal Thermal Nociception. Honjo K, et al. Cell Rep, 2016 Jul 12. PMID 27346357, Free PMC Article
    3. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article
    4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of transcription elongation by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Cdc73/Paf1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of Cdc73/Paf1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6220-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13691707..13693369 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137053.2 → NP_610897.1  uncharacterized protein Dmel_CG6220 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610897.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9G9, Q8T3R1
      Related
      FBpp0086776
      Conserved Domains (2) summary
      pfam05179
      Location:190 → 344
      CDC73_C; RNA pol II accessory factor, Cdc73 family, C-terminal
      pfam16050
      Location:5 → 134
      CDC73_N; Paf1 complex subunit CDC73 N-terminal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z9G9 A1Z9G9
    Q8T3R1 Q8T3R1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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