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    CG6766 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34619, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6766provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032398
    Locus tag
    Dmel_CG6766
    See related
    AllianceGenome:FB:FBgn0032398
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg6766; Dmel\CG6766
    Summary
    Predicted to be involved in retrograde protein transport, ER to cytosol. Located in endomembrane system. Is expressed in several structures, including adult head; central brain primordium; embryonic/larval midgut primordium; ganglia; and mesoderm. Orthologous to human ERLEC1 (endoplasmic reticulum lectin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6766 in Genome Data Viewer
    Location:
    33B10-33B10; 2-45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12038631..12040689, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12038631..12040689, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Dietary and metabolic glutamate transporter Neighboring gene uncharacterized protein Neighboring gene Translocase of outer membrane 70 Neighboring gene antisense RNA:CR46070 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models. Huang HW, et al. Cell Rep, 2018 Feb 6. PMID 29425495, Free PMC Article
    2. New candidate genes for heat resistance in Drosophila melanogaster are regulated by HSF. Jensen LT, et al. Cell Stress Chaperones, 2008 Summer. PMID 18759003, Free PMC Article
    3. Glial ferritin maintains neural stem cells via transporting iron required for self-renewal in Drosophila. Ma Z, et al. Elife, 2024 Sep 10. PMID 39255019, Free PMC Article
    4. FoxO suppresses endoplasmic reticulum stress to inhibit growth of Tsc1-deficient tissues under nutrient restriction. Gupta A, et al. Elife, 2020 Jun 11. PMID 32525804, Free PMC Article
    5. Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED. Hadžić T, et al. Nucleic Acids Res, 2015 Feb 27. PMID 25634895, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in ERAD pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endoplasmic reticulum unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retrograde protein transport, ER to cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    is_active_in endoplasmic reticulum lumen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6766-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      12038631..12040689 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135693.2 → NP_609537.1  uncharacterized protein Dmel_CG6766 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609537.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKC7
      Related
      FBpp0079892
      Conserved Domains (1) summary
      pfam07915
      Location:355 → 428
      PRKCSH; Glucosidase II beta subunit-like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MQY6 Q8MQY6
    Q9VKC7 Q9VKC7

    Gene LinkOut

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