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    pall pallbearer [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39104, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pallprovided by FlyBase
    Official Full Name
    pallbearerprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036005
    Locus tag
    Dmel_CG3428
    See related
    AllianceGenome:FB:FBgn0036005
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3428; Dmel\CG3428; FBXO1; Pall; PALL
    Summary
    Involved in protein polyubiquitination. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in embryonic/larval plasmatocyte. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 100. Orthologous to human FBXO28 (F-box protein 28). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See pall in Genome Data Viewer
    Location:
    67B10-67B10; 3-29 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9486448..9487790, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9479548..9480890, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ubiquitin carboxy-terminal hydrolase L5 Neighboring gene Jumonji, AT rich interactive domain 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Requirement for a Drosophila E3-ubiquitin ligase in phagocytosis of apoptotic cells. Silva E, et al. Immunity, 2007 Oct. PMID 17936033
    2. SnapShot: F box proteins I. Skaar JR, et al. Cell, 2009 Jun 12. PMID 19524517
    3. The Pallbearer E3 ligase promotes actin remodeling via RAC in efferocytosis by degrading the ribosomal protein S6. Xiao H, et al. Dev Cell, 2015 Jan 12. PMID 25533207, Free PMC Article
    4. Macrophage Functions in Tissue Patterning and Disease: New Insights from the Fly. Wood W, et al. Dev Cell, 2017 Feb 6. PMID 28171746, Free PMC Article
    5. FipoQ/FBXO33, a Cullin-1-based ubiquitin ligase complex component modulates ubiquitination and solubility of polyglutamine disease protein. Chen ZS, et al. J Neurochem, 2019 Jun. PMID 30685895

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
    Inferred from Sequence Model
    more info
    		  
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein polyubiquitination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    pallbearer
    Names
    CG3428-PA
    pall-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9486448..9487790 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140068.3 → NP_648325.2  pallbearer [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648325.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RF4, Q9VT01
      Related
      FBpp0076199
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95RF4 Q95RF4
    Q9VT01 Q9VT01

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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