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    CG10339 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37854, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10339provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034972
    Locus tag
    Dmel_CG10339
    See related
    AllianceGenome:FB:FBgn0034972
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10339
    Summary
    Predicted to enable neurexin family protein binding activity and signaling receptor activity. Predicted to be involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Predicted to be active in cell surface and postsynaptic membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human NLGN4X (neuroligin 4 X-linked) and NLGN4Y (neuroligin 4 Y-linked). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10339 in Genome Data Viewer
    Location:
    60B8-60B8; 2-106 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24078234..24080527, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19965757..19968050, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Glycerol-3-phosphate acyltransferase 4 Neighboring gene Muscle LIM protein at 60A Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Drosophila mini-me, a gene required for cell proliferation and survival. Jones C, et al. Genetics, 2006 Jun. PMID 16547096, Free PMC Article
    2. Whole-genome expression analysis in the third instar larval midgut of Drosophila melanogaster. Harrop TW, et al. G3 (Bethesda), 2014 Sep 5. PMID 25193493, Free PMC Article
    3. Identification of novel genes associated with longevity in Drosophila melanogaster - a computational approach. Hall BS, et al. Aging (Albany NY), 2019 Dec 3. PMID 31794428, Free PMC Article
    4. Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway. Deshpande R, et al. G3 (Bethesda), 2022 Nov 4. PMID 35781508, Free PMC Article
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in septate junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in tricellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10339-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24078234..24080527 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138037.3 → NP_611881.1  uncharacterized protein Dmel_CG10339 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611881.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V510, Q9W1B3
      Related
      FBpp0072195
      Conserved Domains (1) summary
      pfam00135
      Location:30 → 560
      COesterase; Carboxylesterase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W1B3 Q9W1B3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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