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    Arglu1 Arginine and glutamate rich 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34320, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Arglu1provided by FlyBase
    Official Full Name
    Arginine and glutamate rich 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0051712
    Locus tag
    Dmel_CG31712
    See related
    AllianceGenome:FB:FBgn0051712
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31712; CG5879; dArglu1; Dmel\CG31712
    Summary
    Enables U1 snRNP binding activity and pre-mRNA binding activity. Located in nucleus. Orthologous to human ARGLU1 (arginine and glutamate rich 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Arglu1 in Genome Data Viewer
    Location:
    30F1-30F1; 2-38 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9934767..9938134, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9934767..9938134, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 30F Neighboring gene antisense RNA:CR45007 Neighboring gene Diadenosine tetraphosphatase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA. Chan SN, et al. EMBO Rep, 2023 Feb 6. PMID 36533631, Free PMC Article
    2. Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. Rehwinkel J, et al. Mol Cell Biol, 2006 Apr. PMID 16581772, Free PMC Article
    3. Gene expression profiling of brakeless mutant Drosophila embryos. Crona F, et al. Data Brief, 2015 Dec. PMID 26509186, Free PMC Article
    4. Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing. Mazloomian A, et al. RNA Biol, 2015. PMID 26512413, Free PMC Article
    5. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables U1 snRNP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pre-mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arginine and glutamate rich 1
    Names
    Arglu1-PA
    Arglu1-PB
    CG31712-PA
    CG31712-PB
    arginine and glutamate-rich protein 1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9934767..9938134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135483.5 → NP_609327.3  arginine and glutamate rich 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609327.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8T0F4, Q9VL63
      Conserved Domains (1) summary
      pfam15346
      Location:135 → 285
      ARGLU; Arginine and glutamate-rich 1

    2. NM_001273379.1 → NP_001260308.1  arginine and glutamate rich 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260308.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PB85
      Conserved Domains (2) summary
      pfam15346
      Location:135 → 189
      ARGLU; Arginine and glutamate-rich 1
      cl21478
      Location:123 → 187
      ATP-synt_B; ATP synthase B/B' CF(0)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PB85 M9PB85
    Q9VL63.3 Q9VL63

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