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    Reep4 receptor accessory protein 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306014, updated on 27-Nov-2024

    Summary

    Official Symbol
    Reep4provided by RGD
    Official Full Name
    receptor accessory protein 4provided by RGD
    Primary source
    RGD:1306561
    See related
    EnsemblRapid:ENSRNOG00000011373 AllianceGenome:RGD:1306561
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306561
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in endoplasmic reticulum tubular network organization and mitotic nuclear membrane reassembly. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytoplasmic microtubule; endoplasmic reticulum membrane; and endoplasmic reticulum tubular network. Orthologous to human REEP4 (receptor accessory protein 4). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Lung (RPKM 121.1), Thymus (RPKM 75.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Reep4 in Genome Data Viewer
    Location:
    15p11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (52030022..52033229)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (45620317..45623524)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (52235283..52238490)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene leucine-rich repeat LGI family, member 3 Neighboring gene uncharacterized LOC134482145 Neighboring gene HR upstream open reading frame Neighboring gene HR, lysine demethylase and nuclear receptor corepressor Neighboring gene nudix hydrolase 18

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC116080

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endoplasmic reticulum tubular network organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitotic nuclear membrane reassembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic nuclear membrane reassembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in nuclear envelope organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear envelope organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasmic microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum tubular network IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    receptor expression-enhancing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025279.1NP_001020450.1  receptor expression-enhancing protein 4

      See identical proteins and their annotated locations for NP_001020450.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097957
      UniProtKB/Swiss-Prot
      Q4QQW1
      UniProtKB/TrEMBL
      A6HTL3
      Related
      ENSRNOP00000015169.4, ENSRNOT00000015169.8
      Conserved Domains (2) summary
      PRK11675
      Location:211243
      PRK11675; LexA regulated protein; Provisional
      pfam03134
      Location:1994
      TB2_DP1_HVA22; TB2/DP1, HVA22 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      52030022..52033229
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)