U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171521, updated on 3-Dec-2024

    Summary

    Symbol
    Cyp2c13provided by RGD
    Full Name
    cytochrome P450, family 2, subfamily c, polypeptide 13provided by RGD
    Primary source
    RGD:620363
    See related
    EnsemblRapid:ENSRNOG00000049464 AllianceGenome:RGD:620363
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cyp2c38
    Summary
    Predicted to enable arachidonate epoxygenase activity; heme binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in epoxygenase P450 pathway and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 2978.9) See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cyp2c13 in Genome Data Viewer
    Location:
    1q53
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (248706787..248787239, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (238786764..238867195, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (258796624..258877023, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene igE-binding protein-like Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 12 Neighboring gene uncharacterized LOC134485236 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC114253

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in organic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in xenobiotic metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cytochrome P450 2C13, male-specific
    Names
    CYP2C13 (+)
    CYPIIC13
    P-450g
    P450-G
    UT-5
    cytochrome P-450g
    cytochrome P450 2C13, male-specific-like
    cytochrome P450 g (+)
    cytochrome P450, 2c38
    cytochrome P450-G
    cytochrome P450-UT-5
    NP_612523.1
    XP_038946817.1
    XP_038946856.1
    XP_038946894.1
    XP_063133702.1
    XP_063133714.1
    XP_063133724.1
    XP_063133732.1
    XP_063133747.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138514.1NP_612523.1  cytochrome P450 2C13, male-specific

      See identical proteins and their annotated locations for NP_612523.1

      Status: PROVISIONAL

      Source sequence(s)
      M32277
      UniProtKB/Swiss-Prot
      P20814, P22693, Q64587
      UniProtKB/TrEMBL
      M0RD38, Q5I0P5
      Related
      ENSRNOP00000067531.1, ENSRNOT00000071633.5
      Conserved Domains (1) summary
      pfam00067
      Location:30487
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      248706787..248787239 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277632.1XP_063133702.1  cytochrome P450 2C13, male-specific isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZKW5
    2. XM_063277644.1XP_063133714.1  cytochrome P450 2C13, male-specific isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZKW5
    3. XM_039090889.2XP_038946817.1  cytochrome P450 2C13, male-specific isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZKW5
      Conserved Domains (1) summary
      cd20665
      Location:61431
      CYP2C-like; cytochrome P450 family 2, subfamily C, and similar cytochrome P450s
    4. XM_063277654.1XP_063133724.1  cytochrome P450 2C13, male-specific isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZKW5
      Related
      ENSRNOP00000078469.1, ENSRNOT00000118870.2
    5. XM_063277662.1XP_063133732.1  cytochrome P450 2C13, male-specific isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZKW5
    6. XM_063277677.1XP_063133747.1  cytochrome P450 2C13, male-specific isoform X5

    7. XM_039090966.2XP_038946894.1  cytochrome P450 2C13, male-specific isoform X7

      Conserved Domains (1) summary
      cl41757
      Location:61273
      cytochrome_P450; cytochrome P450 (CYP) superfamily
    8. XM_039090928.2XP_038946856.1  cytochrome P450 2C13, male-specific isoform X6

      Conserved Domains (1) summary
      cl41757
      Location:61281
      cytochrome_P450; cytochrome P450 (CYP) superfamily