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    PRPF18 pre-mRNA processing factor 18 [ Homo sapiens (human) ]

    Gene ID: 8559, updated on 10-Dec-2024

    Summary

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    Official Symbol
    PRPF18provided by HGNC
    Official Full Name
    pre-mRNA processing factor 18provided by HGNC
    Primary source
    HGNC:HGNC:17351
    See related
    Ensembl:ENSG00000165630 MIM:604993; AllianceGenome:HGNC:17351
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PRP18; hPrp18
    Summary
    Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in fat (RPKM 3.4), brain (RPKM 3.1) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See PRPF18 in Genome Data Viewer
    Location:
    10p13
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (13586965..13655929)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (13599966..13668950)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (13628965..13697929)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene BEN domain containing 7 Neighboring gene uncharacterized LOC105376422 Neighboring gene BEND7 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3055 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:13629435-13630030 Neighboring gene ribosomal protein L6 pseudogene 24 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3056 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3057 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:13715567-13716091 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2156 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:13732519-13733075 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2157 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:13749502-13750237 Neighboring gene uncharacterized LOC124902379 Neighboring gene uncharacterized LOC105376426 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:13753704-13754570 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:13754571-13755435 Neighboring gene FERM domain containing 4A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3061 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2158 Neighboring gene RNA, 5S ribosomal pseudogene 301

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Solution structure of the splicing factor motif of the human Prp18 protein. He F, et al. Proteins, 2012 Mar. PMID 22213562
    2. Pre-mRNA Processing Factor Prp18 Is a Stimulatory Factor of Influenza Virus RNA Synthesis and Possesses Nucleoprotein Chaperone Activity. Minakuchi M, et al. J Virol, 2017 Feb 1. PMID 27852861, Free PMC Article
    3. Stages in the second reaction of pre-mRNA splicing: the final step is ATP independent. Horowitz DS, et al. Genes Dev, 1993 Feb. PMID 8436300
    4. A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor. Horowitz DS, et al. Genes Dev, 1997 Jan 1. PMID 9000057
    5. Identification of a novel locus associated with skin colour in African-admixed populations. Hernandez-Pacheco N, et al. Sci Rep, 2017 Mar 16. PMID 28300201, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results validated the association of two previously known skin pigmentation genes, SLC24A5 (minimum p = 2.62 x 10(-14), rs1426654) and SLC45A2 (minimum p = 9.71 x 10(-10), rs16891982), and revealed the intergenic region of BEND7 and PRPF18 as a novel locus associated with this trait (minimum p = 4.58 x 10(-9), rs6602666).
      Title: Identification of a novel locus associated with skin colour in African-admixed populations.
    2. We identified the pre-mRNA processing factor Prp18 as a stimulatory factor for influenza virus RNA synthesis. Prp18 facilitates the elongation reaction of viral polymerases by preventing the deleterious annealing of newly synthesized RNA to the template. Prp18 functions as a chaperone for NP to stimulate the formation of NP-RNA complexes.
      Title: Pre-mRNA Processing Factor Prp18 Is a Stimulatory Factor of Influenza Virus RNA Synthesis and Possesses Nucleoprotein Chaperone Activity.
    3. Presented is solution structure of the splicing factor motif of hPrp18, which forms a compact fold with two a helices interacting head-to-tail and a fixed linker loop.
      Title: Solution structure of the splicing factor motif of the human Prp18 protein.
    4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    5. Observational study of gene-disease association. (HuGE Navigator)
      Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.
    EBI GWAS Catalog
    Lupus nephritis susceptibility Loci in women with systemic lupus erythematosus.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ10210, FLJ30455, FLJ42487, FLJ43137, DKFZp434L162, DKFZp686H1792

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA splicing TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in generation of catalytic spliceosome for second transesterification step IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA processing TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U2-type post-spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of spliceosomal complex TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-mRNA-splicing factor 18
    Names
    PRP18 homolog
    PRP18 pre-mRNA processing factor 18 homolog
    PRP18 pre-mRNA processing factor 18 homolog(PRPF18)

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395875.1 → NP_001382804.1  pre-mRNA-splicing factor 18 isoform 1

      Status: REVIEWED

      Source sequence(s)
      AL157392
      UniProtKB/TrEMBL
      B2RBU0
      Conserved Domains (2) summary
      smart00500
      Location:88 → 131
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      pfam02840
      Location:200 → 336
      Prp18; Prp18 domain

    2. NM_001395876.1 → NP_001382805.1  pre-mRNA-splicing factor 18 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AL157392
      UniProtKB/TrEMBL
      B2RBU0
      Conserved Domains (2) summary
      smart00500
      Location:73 → 116
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      pfam02840
      Location:185 → 321
      Prp18; Prp18 domain

    3. NM_001395877.1 → NP_001382806.1  pre-mRNA-splicing factor 18 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AL157392
      UniProtKB/TrEMBL
      B2RBU0
      Conserved Domains (1) summary
      smart00500
      Location:79 → 122
      SFM; Splicing Factor Motif, present in Prp18 and Pr04

    4. NM_001395878.1 → NP_001382807.1  pre-mRNA-splicing factor 18 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AL157392
      UniProtKB/TrEMBL
      B2RBU0
      Conserved Domains (2) summary
      smart00500
      Location:64 → 107
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      pfam02840
      Location:176 → 312
      Prp18; Prp18 domain

    5. NM_001395879.1 → NP_001382808.1  pre-mRNA-splicing factor 18 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL157392
      UniProtKB/TrEMBL
      B2RBU0
      Conserved Domains (1) summary
      smart00500
      Location:79 → 122
      SFM; Splicing Factor Motif, present in Prp18 and Pr04

    6. NM_001395880.1 → NP_001382809.1  pre-mRNA-splicing factor 18 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AL157392
      UniProtKB/TrEMBL
      B2RBU0
      Conserved Domains (1) summary
      smart00500
      Location:88 → 131
      SFM; Splicing Factor Motif, present in Prp18 and Pr04

    7. NM_001395881.1 → NP_001382810.1  pre-mRNA-splicing factor 18 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AL157392
      UniProtKB/TrEMBL
      B2RBU0
      Conserved Domains (2) summary
      smart00500
      Location:79 → 122
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      pfam02840
      Location:193 → 280
      Prp18; Prp18 domain

    8. NM_001395882.1 → NP_001382811.1  pre-mRNA-splicing factor 18 isoform 9

      Status: REVIEWED

      Source sequence(s)
      AL157392
      UniProtKB/TrEMBL
      B2RBU0

    9. NM_001395883.1 → NP_001382812.1  pre-mRNA-splicing factor 18 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AL157392
      Conserved Domains (1) summary
      smart00500
      Location:73 → 116
      SFM; Splicing Factor Motif, present in Prp18 and Pr04

    10. NM_001395884.1 → NP_001382813.1  pre-mRNA-splicing factor 18 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AL157392
      Conserved Domains (1) summary
      smart00500
      Location:79 → 122
      SFM; Splicing Factor Motif, present in Prp18 and Pr04

    11. NM_001395885.1 → NP_001382814.1  pre-mRNA-splicing factor 18 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL157392
      Conserved Domains (1) summary
      smart00500
      Location:3 → 46
      SFM; Splicing Factor Motif, present in Prp18 and Pr04

    12. NM_001395886.1 → NP_001382815.1  pre-mRNA-splicing factor 18 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL157392
      Conserved Domains (1) summary
      smart00500
      Location:3 → 46
      SFM; Splicing Factor Motif, present in Prp18 and Pr04

    13. NM_001395887.1 → NP_001382816.1  pre-mRNA-splicing factor 18 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AL157392
      Conserved Domains (1) summary
      smart00500
      Location:64 → 107
      SFM; Splicing Factor Motif, present in Prp18 and Pr04

    14. NM_003675.4 → NP_003666.1  pre-mRNA-splicing factor 18 isoform 2

      See identical proteins and their annotated locations for NP_003666.1

      Status: REVIEWED

      Source sequence(s)
      AI580379, AL157392, AU142253, BC000794, BC002572
      Consensus CDS
      CCDS7100.1
      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0
      Related
      ENSP00000367835.3, ENST00000378572.8
      Conserved Domains (2) summary
      smart00500
      Location:79 → 122
      SFM; Splicing Factor Motif, present in Prp18 and Pr04
      pfam02840
      Location:191 → 327
      Prp18; Prp18 domain

    RNA

    1. NR_172904.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL157392

    2. NR_172905.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL157392

    3. NR_172906.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL157392

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      13586965..13655929
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047425923.1 → XP_047281879.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    2. XM_047425933.1 → XP_047281889.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    3. XM_047425943.1 → XP_047281899.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    4. XM_047425938.1 → XP_047281894.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    5. XM_047425944.1 → XP_047281900.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    6. XM_047425947.1 → XP_047281903.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    7. XM_047425949.1 → XP_047281905.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    8. XM_047425926.1 → XP_047281882.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    9. XM_047425936.1 → XP_047281892.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    10. XM_047425929.1 → XP_047281885.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    11. XM_047425934.1 → XP_047281890.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    12. XM_047425927.1 → XP_047281883.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    13. XM_047425940.1 → XP_047281896.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    14. XM_047425946.1 → XP_047281902.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    15. XM_047425948.1 → XP_047281904.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    16. XM_047425950.1 → XP_047281906.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    17. XM_047425953.1 → XP_047281909.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    18. XM_047425931.1 → XP_047281887.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    19. XM_047425932.1 → XP_047281888.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    20. XM_047425939.1 → XP_047281895.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    21. XM_047425945.1 → XP_047281901.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    22. XM_047425935.1 → XP_047281891.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    23. XM_047425957.1 → XP_047281913.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    24. XM_047425959.1 → XP_047281915.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    25. XM_047425928.1 → XP_047281884.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    26. XM_047425930.1 → XP_047281886.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    27. XM_047425942.1 → XP_047281898.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    28. XM_047425937.1 → XP_047281893.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    29. XM_047425951.1 → XP_047281907.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    30. XM_047425958.1 → XP_047281914.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    31. XM_047425954.1 → XP_047281910.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    32. XM_047425961.1 → XP_047281917.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    33. XM_047425960.1 → XP_047281916.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    34. XM_047425955.1 → XP_047281911.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    35. XM_047425962.1 → XP_047281918.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    36. XM_047425924.1 → XP_047281880.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    37. XM_047425925.1 → XP_047281881.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    38. XM_047425952.1 → XP_047281908.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    39. XM_047425964.1 → XP_047281920.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    40. XM_047425941.1 → XP_047281897.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    41. XM_047425956.1 → XP_047281912.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    42. XM_047425963.1 → XP_047281919.1  pre-mRNA-splicing factor 18 isoform X2

      UniProtKB/Swiss-Prot
      Q5T9P9, Q99633, Q9BUI9
      UniProtKB/TrEMBL
      B2RBU0

    43. XM_047425966.1 → XP_047281922.1  pre-mRNA-splicing factor 18 isoform X4

      UniProtKB/TrEMBL
      B2RBU0

    44. XM_047425965.1 → XP_047281921.1  pre-mRNA-splicing factor 18 isoform X3

      UniProtKB/TrEMBL
      B2RBU0

    45. XM_047425967.1 → XP_047281923.1  pre-mRNA-splicing factor 18 isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      13599966..13668950
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054367056.1 → XP_054223031.1  pre-mRNA-splicing factor 18 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99633.1 GenPept UniProtKB/Swiss-Prot:Q99633

    Gene LinkOut

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