MBP1 transcription factor MBP1 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: MBP1
Official Full Name: transcription factor MBP1
Primary source: SGD:S000002214
Locus tag: YDL056W
See related: AllianceGenome:SGD:S000002214; FungiDB:YDL056W; VEuPathDB:YDL056W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in G1/S transition of mitotic cell cycle and positive regulation of transcription by RNA polymerase II. Acts upstream of or within maintenance of translational fidelity. Located in nucleus. Part of MBF transcription complex. [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Deletion of the MBP1 Gene, Involved in the Cell Cycle, Affects Respiration and Pseudohyphal Differentiation in Saccharomyces cerevisiae.
Title: Deletion of the MBP1 Gene, Involved in the Cell Cycle, Affects Respiration and Pseudohyphal Differentiation in Saccharomyces cerevisiae.
TORC1 regulates G1/S transition and cell proliferation via the E2F homologs MBF and SBF in yeast.
Title: TORC1 regulates G1/S transition and cell proliferation via the E2F homologs MBF and SBF in yeast.
Deletion of Mbp1 enhances transcription, suggesting that Mbp1 can also function as transcriptional repressor.
Title: High functional overlap between MluI cell-cycle box binding factor and Swi4/6 cell-cycle box binding factor in the G1/S transcriptional program in Saccharomyces cerevisiae.
the binding site for Xbp1 is present in the target genes of Swi4 and Mbp1 and is conserved phylogenetically
Title: Identification of target genes of a yeast transcriptional repressor.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IMP Inferred from Mutant Phenotype more info	PubMed
enables sequence-specific DNA binding	HDA more info	PubMed

Process	Evidence Code	Pubs
involved_in G1/S transition of mitotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within maintenance of translational fidelity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of MBF transcription complex	IBA Inferred from Biological aspect of Ancestor more info
part_of MBF transcription complex	IDA Inferred from Direct Assay more info	PubMed
part_of RNA polymerase II transcription regulator complex	IEA Inferred from Electronic Annotation more info
part_of SBF transcription complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	HDA more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_010227.1

Transcription factor; involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain