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    Sult1c3 sulfotransferase family 1C member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 65185, updated on 9-Dec-2024

    Summary

    Symbol
    Sult1c3provided by RGD
    Full Name
    sulfotransferase family 1C member 3provided by RGD
    Primary source
    RGD:3768
    See related
    EnsemblRapid:ENSRNOG00000011269 AllianceGenome:RGD:3768
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Stp2; St1c1; HAST-I; Sult1a2; Sult1c1
    Summary
    Enables aryl sulfotransferase activity. Predicted to be involved in several processes, including 3'-phosphoadenosine 5'-phosphosulfate metabolic process; cholesterol metabolic process; and sulfation. Predicted to act upstream of or within sulfur compound metabolic process. Predicted to be active in cytoplasm. Orthologous to human SULT1C3 (sulfotransferase family 1C member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 1183.2) See more
    Orthologs
    NEW
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    Genomic context

    See Sult1c3 in Genome Data Viewer
    Location:
    9q11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (7548839..7594299, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (7221580..7266991, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (4931038..4978847, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene sulfotransferase family 1C member 2 Neighboring gene sulfotransferase family 1C member 2A like 1 Neighboring gene uncharacterized LOC134480319 Neighboring gene actin, alpha 1, skeletal muscle, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC108652

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables 3'-phosphoadenosine 5'-phosphosulfate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables alcohol sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables aryl sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables aryl sulfotransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables aryl sulfotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables aryl sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables bile-salt sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in 3'-phosphoadenosine 5'-phosphosulfate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cholesterol metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sulfation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sulfur compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within sulfur compound metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sulfur compound metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in xenobiotic metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sulfotransferase 1C1
    Names
    N-hydroxyarylamine sulfotransferase
    N-hydroxylarylamine sulfotransferase
    Phenol sulfotransferase 1c1
    sulfotransferase 1C1-like
    sulfotransferase family 1A, member 2
    sulfotransferase family 1A, phenol-preferring, member 2
    sulfotransferase family, cytosolic, 1C, member 1
    sulfotransferase family, cytosolic, 1C, member 3
    sulfotransferase, phenol preferring 2
    sulphotransferase family cytosolic 1A phenol-preferring member 2
    NP_113920.2
    XP_063123775.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031732.2NP_113920.2  sulfotransferase 1C1

      See identical proteins and their annotated locations for NP_113920.2

      Status: PROVISIONAL

      Source sequence(s)
      BC088125
      UniProtKB/Swiss-Prot
      P50237, Q5M8B5
      UniProtKB/TrEMBL
      A0A0G2K5J0, A6KQA2
      Related
      ENSRNOP00000015189.1, ENSRNOT00000015189.6
      Conserved Domains (1) summary
      pfam00685
      Location:46296
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      7548839..7594299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063267705.1XP_063123775.1  sulfotransferase 1C1 isoform X1

      UniProtKB/Swiss-Prot
      P50237, Q5M8B5
      UniProtKB/TrEMBL
      A0A0G2K5J0, A6KQA2