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    ARG81 Arg81p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854874, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ARG81
    Official Full Name
    Arg81p
    Primary source
    SGD:S000004565
    Locus tag
    YML099C
    See related
    AllianceGenome:SGD:S000004565; FungiDB:YML099C; VEuPathDB:YML099C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ARGR2
    Summary
    Enables transcription coregulator activity. Involved in regulation of arginine metabolic process. Located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ARG81 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (74398..77040, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene trehalose 6-phosphate synthase/phosphatase complex subunit Neighboring gene Taf13p Neighboring gene guanine nucleotide exchange factor VPS9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of the yeast ARGRII gene involved in regulating both anabolism and catabolism of arginine. Dubois E, et al. Mol Gen Genet, 1985. PMID 3884975
    2. Causal Genetic Variation Underlying Metabolome Differences. Swain-Lenz D, et al. Genetics, 2017 Aug. PMID 28652377, Free PMC Article
    3. Regulation of arginine biosynthesis in Saccharomyces cerevisiae: isolation of a cis-dominant, constitutive mutant for ornithine carbamoyltransferase synthesis. Messenguy F. J Bacteriol, 1976 Oct. PMID 789352, Free PMC Article
    4. Characterization of the DNA target site for the yeast ARGR regulatory complex, a sequence able to mediate repression or induction by arginine. De Rijcke M, et al. Mol Cell Biol, 1992 Jan. PMID 1729616, Free PMC Article
    5. Dissection of the bifunctional ARGRII protein involved in the regulation of arginine anabolic and catabolic pathways. Qui HF, et al. Mol Cell Biol, 1991 Apr. PMID 2005903, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Quantitative trait loci analysis suggest that polymorphism in the coding region of GCN1, MDS3, ARG81 and BIO3 could account for differences in nitrogen requirement.
      Title: A genetic approach of wine yeast fermentation capacity in nitrogen-starvation reveals the key role of nitrogen signaling.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transcription coregulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in arginine metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of arginine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Arg81p
    NP_013610.1
    • Zinc finger transcription factor involved in arginine-responsive genes; Zn(2)-Cys(6) binuclear cluster domain type; involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      74398..77040 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182459.1 → NP_013610.1  TPA: Arg81p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013610.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0I6, P05085
      UniProtKB/TrEMBL
      G2WJV8
      Conserved Domains (2) summary
      pfam00172
      Location:19 → 58
      Zn_clus; Fungal Zn(2)-Cys(6) binuclear cluster domain
      pfam11951
      Location:395 → 878
      Fungal_trans_2; Fungal specific transcription factor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P05085.3

    Gene LinkOut

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