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    RPL34A ribosomal 60S subunit protein L34A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL34A
    Official Full Name
    ribosomal 60S subunit protein L34A
    Primary source
    SGD:S000002135
    Locus tag
    YER056C-A
    See related
    AllianceGenome:SGD:S000002135; FungiDB:YER056C-A; VEuPathDB:YER056C-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be a structural constituent of ribosome. Involved in ribosome biogenesis. Part of preribosome, large subunit precursor. Orthologous to human RPL34 (ribosomal protein L34). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL34A in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_001137.3 (269423..270185, complement)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene ATP phosphoribosyltransferase Neighboring gene purine-cytosine permease Neighboring gene putative isoleucine biosynthesis protein HMF1 Neighboring gene Pet117p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity. Maitra N, et al. Elife, 2020 May 20. PMID 32432546, Free PMC Article
    2. Roles of Ebp2 and ribosomal protein L36 in ribosome biogenesis in Saccharomyces cerevisiae. Wan K, et al. Curr Genet, 2015 Feb. PMID 25119672
    3. Introns within ribosomal protein genes regulate the production and function of yeast ribosomes. Parenteau J, et al. Cell, 2011 Oct 14. PMID 22000012
    4. Ribosomal proteins produced in excess are degraded by the ubiquitin-proteasome system. Sung MK, et al. Mol Biol Cell, 2016 Sep 1. PMID 27385339, Free PMC Article
    5. A High-Copy Suppressor Screen Reveals a Broad Role of Prefoldin-like Bud27 in the TOR Signaling Pathway in Saccharomyces cerevisiae. Gutiérrez-Santiago F, et al. Genes (Basel), 2022 Apr 24. PMID 35627133, Free PMC Article

    See all (73) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in ribosome biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosome biogenesis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of preribosome, large subunit precursor IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L34A
    NP_010977.2
    • Ribosomal 60S subunit protein L34A; homologous to mammalian ribosomal protein L34, no bacterial homolog; RPL34A has a paralog, RPL34B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      269423..270185 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180036.1 → NP_010977.2  TPA: ribosomal 60S subunit protein L34A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010977.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLW0, P87262, Q03189
      UniProtKB/TrEMBL
      A6ZR09, B3LS71, C7GVY0, C8Z762, G2WCU3, N1P3D8
      Conserved Domains (1) summary
      pfam01199
      Location:1 → 94
      Ribosomal_L34e; Ribosomal protein L34e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P87262.1

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