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    psm1 mitotic/meiotic cohesin complex ATPase subunit Psm1/Smc1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540557, updated on 18-Sep-2024

    Summary

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    Official Symbol
    psm1
    Official Full Name
    mitotic/meiotic cohesin complex ATPase subunit Psm1/Smc1
    Primary source
    PomBase:SPBC29A10.04
    Locus tag
    SPOM_SPBC29A10.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    smc1
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    Genomic context

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    See psm1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (2540716..2545157)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene histone H3-H4 chaperone, CAF assembly factor (CAF-1) complex subunit A Pcf1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene exonuclease I Exo1 Neighboring gene ncRNA Neighboring gene nuclear pore protein Ely5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Condensin but not cohesin SMC heterodimer induces DNA reannealing through protein-protein assembly. Sakai A, et al. EMBO J, 2003 Jun 2. PMID 12773391, Free PMC Article
    2. DNA Binding by the Mis4(Scc2) Loader Promotes Topological DNA Entrapment by the Cohesin Ring. Kurokawa Y, et al. Cell Rep, 2020 Nov 10. PMID 33176147
    3. Suppressor mutation analysis combined with 3D modeling explains cohesin's capacity to hold and release DNA. Xu X, et al. Proc Natl Acad Sci U S A, 2018 May 22. PMID 29735656, Free PMC Article
    4. Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation. Phadnis N, et al. PLoS Genet, 2015 May. PMID 25993311, Free PMC Article
    5. Biochemical reconstitution of topological DNA binding by the cohesin ring. Murayama Y, et al. Nature, 2014 Jan 16. PMID 24291789, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Mutations in Mus81 and Eme1 endonuclease prevent methylation of Psm1 at K536 and K1200.
      Title: Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    contributes_to topological DNA co-entrapment activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    contributes_to topological DNA co-entrapment activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin looping IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mitotic sister chromatid cohesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of cohesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in condensed chromosome, centromeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of meiotic cohesin complex NAS
    Non-traceable Author Statement
    more info
    		  
    part_of mitotic cohesin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mitotic/meiotic cohesin complex ATPase subunit Psm1/Smc1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2540716..2545157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021960.3 → NP_596049.2  mitotic/meiotic cohesin complex ATPase subunit Psm1/Smc1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596049.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94383
      Conserved Domains (1) summary
      COG1196
      Location:3 → 1228
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    Nucleotide Protein
    Heading Accession and Version

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