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    his2 histidinol dehydrogenase His2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539650, updated on 18-Sep-2024

    Summary

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    Official Symbol
    his2
    Official Full Name
    histidinol dehydrogenase His2
    Primary source
    PomBase:SPBC1711.13
    Locus tag
    SPOM_SPBC1711.13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See his2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2159845..2161291)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene acylpeptide hydrolase Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene meiotic recombination protein Rec15 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide screen reveals novel mechanisms for regulating cobalt uptake and detoxification in fission yeast. Ryuko S, et al. Mol Genet Genomics, 2012 Aug. PMID 22806344
    2. Development of a genetic transformation system using new selectable markers for fission yeast Schizosaccharomyces pombe. Fujita Y, et al. Yeast, 2005 Feb. PMID 15704224
    3. Autophagy is required for efficient meiosis progression and proper meiotic chromosome segregation in fission yeast. Matsuhara H, et al. Genes Cells, 2016 Jan. PMID 26696398
    4. Genetic Mapping in SCHIZOSACCHAROMYCES POMBE by Mitotic and Meiotic Analysis and Induced Haploidization. Kohli J, et al. Genetics, 1977 Nov. PMID 17248775, Free PMC Article
    5. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables histidinol dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histidinol dehydrogenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-histidine biosynthetic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in L-histidine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in L-histidine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    histidinol dehydrogenase His2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2159845..2161291
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021792.3 → NP_595886.1  histidinol dehydrogenase His2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595886.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P777
      Conserved Domains (2) summary
      TIGR00069
      Location:39 → 435
      hisD; histidinol dehydrogenase
      pfam00815
      Location:25 → 435
      Histidinol_dh; Histidinol dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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