Tmem30b transmembrane protein 30B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tmem30bprovided by MGI
Official Full Name: transmembrane protein 30Bprovided by MGI
Primary source: MGI:MGI:2442082
See related: Ensembl:ENSMUSG00000034435 AllianceGenome:MGI:2442082
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 9130011B11Rik
Summary: Predicted to enable aminophospholipid flippase activity. Predicted to be involved in aminophospholipid transport; phospholipid translocation; and positive regulation of protein exit from endoplasmic reticulum. Predicted to be part of phospholipid-translocating ATPase complex. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including alimentary system; endocrine gland; forelimb bud; liver; and male reproductive gland or organ. Orthologous to human TMEM30B (transmembrane protein 30B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human all
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Genomic context

Location:: 12 C3; 12 30.65 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (73589888..73593169, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (73543114..73546395, complement)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CREB3L1 deficiency impairs odontoblastic differentiation and molar dentin deposition partially through the TMEM30B.
Title: CREB3L1 deficiency impairs odontoblastic differentiation and molar dentin deposition partially through the TMEM30B.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (1)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:236868

NoName (e-PCR)
- UniSTS:236869

BB210689 (e-PCR)
- UniSTS:208822

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables aminophospholipid flippase activity	IEA Inferred from Electronic Annotation more info
enables aminophospholipid flippase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in aminophospholipid translocation	IEA Inferred from Electronic Annotation more info
involved_in aminophospholipid transport	ISO Inferred from Sequence Orthology more info
involved_in phospholipid translocation	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of protein exit from endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of protein exit from endoplasmic reticulum	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
part_of phospholipid-translocating ATPase complex	IEA Inferred from Electronic Annotation more info
part_of phospholipid-translocating ATPase complex	ISO Inferred from Sequence Orthology more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: cell cycle control protein 50B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.