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    TSR1 TSR1 ribosome maturation factor [ Bos taurus (domestic cattle) ]

    Gene ID: 510820, updated on 27-Dec-2024

    Summary

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    Official Symbol
    TSR1provided by VGNC
    Official Full Name
    TSR1 ribosome maturation factorprovided by VGNC
    Primary source
    VGNC:VGNC:36447
    See related
    BGD:BT15052; Ensembl:ENSBTAG00000004225
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TSR1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (23296361..23306746, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene SMG6 nonsense mediated mRNA decay factor Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene small nucleolar RNA SNORD91 family Neighboring gene small nucleolar RNA SNORD91 family Neighboring gene serine racemase Neighboring gene small G protein signaling modulator 2 Neighboring gene MAX network transcriptional repressor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC166095

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables U3 snoRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of preribosome, small subunit precursor IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pre-rRNA-processing protein TSR1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101933.1 → NP_001095403.1  pre-rRNA-processing protein TSR1 homolog

      See identical proteins and their annotated locations for NP_001095403.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149918
      UniProtKB/TrEMBL
      A6QQN4, F1MSR6
      Conserved Domains (3) summary
      smart00785
      Location:80 → 161
      AARP2CN; AARP2CN (NUC121) domain
      pfam04950
      Location:340 → 627
      RIBIOP_C; 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
      cl00388
      Location:308 → 335
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      23296361..23306746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220084.5 → XP_005220141.2  pre-rRNA-processing protein TSR1 homolog isoform X1

      UniProtKB/TrEMBL
      F1MSR6
      Related
      ENSBTAP00000005534.7, ENSBTAT00000005534.7
      Conserved Domains (3) summary
      smart00785
      Location:228 → 309
      AARP2CN; AARP2CN (NUC121) domain
      pfam04950
      Location:488 → 775
      RIBIOP_C; 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
      cl00388
      Location:457 → 483
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    2. XM_059877899.1 → XP_059733882.1  pre-rRNA-processing protein TSR1 homolog isoform X3

      UniProtKB/TrEMBL
      F1MSR6

    3. XM_024979914.2 → XP_024835682.1  pre-rRNA-processing protein TSR1 homolog isoform X2

      UniProtKB/TrEMBL
      F1MSR6
      Conserved Domains (3) summary
      smart00785
      Location:106 → 187
      AARP2CN; AARP2CN (NUC121) domain
      pfam04950
      Location:366 → 653
      RIBIOP_C; 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
      cl00388
      Location:335 → 361
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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