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    ESD esterase D [ Bos taurus (domestic cattle) ]

    Gene ID: 535653, updated on 30-Jan-2025

    Summary

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    Official Symbol
    ESDprovided by VGNC
    Official Full Name
    esterase Dprovided by VGNC
    Primary source
    VGNC:VGNC:28600
    See related
    BGD:BT19353; EnsemblRapid:ENSBTAG00070026324
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ESD in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (16723866..16744753, complement)

    Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-2285o-1 Neighboring gene microRNA mir-2285av Neighboring gene leucine rich repeats and calponin homology domain containing 1 Neighboring gene uncharacterized LOC132346740 Neighboring gene 5-hydroxytryptamine receptor 2A Neighboring gene succinate-CoA ligase ADP-forming subunit beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Physical mapping confirms that sheep chromosome 10 has extensive conserved synteny with cattle chromosome 12 and human chromosome 13. Broad TE, et al. Anim Genet, 1996 Aug. PMID 8856922
    2. Syntenic assignment of human serotonin receptor subtype 2 (HTR2), esterase D (ESD), and fms-related tyrosine kinase (FLT) homologs to bovine chromosome 12. Sun HS, et al. Mamm Genome, 1996 Jul. PMID 8672130
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139609

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables S-formylglutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in formaldehyde catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    S-formylglutathione hydrolase
    Names
    FGH
    esterase D/formylglutathione hydrolase
    NP_001069533.1
    XP_005213716.1
    XP_005213717.1
    XP_005213718.1
    XP_005213719.1
    XP_024855686.1
    XP_024855687.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076065.1 → NP_001069533.1  S-formylglutathione hydrolase

      See identical proteins and their annotated locations for NP_001069533.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123461
      UniProtKB/Swiss-Prot
      Q08E20
      UniProtKB/TrEMBL
      A0AAF6YKW8
      Related
      ENSBTAP00070035365.1, ENSBTAT00070059593.1
      Conserved Domains (1) summary
      cl21494
      Location:2 → 281
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      16723866..16744753 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024999919.2 → XP_024855687.1  S-formylglutathione hydrolase isoform X2

      UniProtKB/Swiss-Prot
      Q08E20
      UniProtKB/TrEMBL
      A0AAF6YKW8
      Conserved Domains (1) summary
      cl21494
      Location:2 → 281
      Abhydrolase; alpha/beta hydrolases

    2. XM_024999918.2 → XP_024855686.1  S-formylglutathione hydrolase isoform X2

      UniProtKB/Swiss-Prot
      Q08E20
      UniProtKB/TrEMBL
      A0AAF6YKW8
      Conserved Domains (1) summary
      cl21494
      Location:2 → 281
      Abhydrolase; alpha/beta hydrolases

    3. XM_005213660.5 → XP_005213717.1  S-formylglutathione hydrolase isoform X1

      See identical proteins and their annotated locations for XP_005213717.1

      UniProtKB/TrEMBL
      A0A3Q1MAU7, A0AAF6YKW8
      Conserved Domains (1) summary
      cl21494
      Location:12 → 291
      Abhydrolase; alpha/beta hydrolases

    4. XM_005213661.4 → XP_005213718.1  S-formylglutathione hydrolase isoform X2

      See identical proteins and their annotated locations for XP_005213718.1

      UniProtKB/Swiss-Prot
      Q08E20
      UniProtKB/TrEMBL
      A0AAF6YKW8
      Conserved Domains (1) summary
      cl21494
      Location:2 → 281
      Abhydrolase; alpha/beta hydrolases

    5. XM_005213662.5 → XP_005213719.1  S-formylglutathione hydrolase isoform X2

      See identical proteins and their annotated locations for XP_005213719.1

      UniProtKB/Swiss-Prot
      Q08E20
      UniProtKB/TrEMBL
      A0AAF6YKW8
      Conserved Domains (1) summary
      cl21494
      Location:2 → 281
      Abhydrolase; alpha/beta hydrolases

    6. XM_005213659.5 → XP_005213716.1  S-formylglutathione hydrolase isoform X1

      See identical proteins and their annotated locations for XP_005213716.1

      UniProtKB/TrEMBL
      A0A3Q1MAU7, A0AAF6YKW8
      Conserved Domains (1) summary
      cl21494
      Location:12 → 291
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08E20.1 GenPept UniProtKB/Swiss-Prot:Q08E20

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