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    PSMB8 proteasome 20S subunit beta 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 282013, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PSMB8provided by VGNC
    Official Full Name
    proteasome 20S subunit beta 8provided by VGNC
    Primary source
    VGNC:VGNC:33452
    See related
    BGD:BT10247; Ensembl:ENSBTAG00000003039
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    LMP7
    Orthologs
    human mouse all
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    Genomic context

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    See PSMB8 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (7173032..7176410, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)-like Neighboring gene uncharacterized LOC132343596 Neighboring gene transporter 1, ATP binding cassette subfamily B member Neighboring gene proteasome 20S subunit beta 9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Expression and regulation of interferon gamma-inducible proteasomal subunits LMP7 and LMP10 in the bovine corpus luteum. Cannon MJ, et al. Biol Reprod, 2003 Apr. PMID 12606494
    2. A radiation hybrid map of BTA23: identification of a chromosomal rearrangement leading to separation of the cattle MHC class II subregions. Band M, et al. Genomics, 1998 Nov 1. PMID 9799592
    3. Comparative analysis of the bovine MHC class IIb sequence identifies inversion breakpoints and three unexpected genes. Childers CP, et al. Anim Genet, 2006 Apr. PMID 16573526
    4. Physical assignment of the bovine MHC class IIa and class IIb genes. Hess M, et al. Cytogenet Cell Genet, 1999. PMID 10449907
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC126938

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables threonine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of proteasome core complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proteasome subunit beta type-8
    Names
    large multifunctional protease 7
    macropain
    proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
    proteasome subunit LMP7
    proteasome subunit beta 8
    proteasome subunit beta-5i
    proteasome subunit, beta type 8
    NP_001035570.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040480.2 → NP_001035570.1  proteasome subunit beta type-8

      Status: PROVISIONAL

      Source sequence(s)
      BC102170
      UniProtKB/TrEMBL
      A0AAF6YKP0
      Related
      ENSBTAP00000003955.6, ENSBTAT00000003955.7
      Conserved Domains (2) summary
      PTZ00488
      Location:37 → 271
      PTZ00488; Proteasome subunit beta type-5; Provisional
      cd03761
      Location:73 → 260
      proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      7173032..7176410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3T112.2 GenPept UniProtKB/Swiss-Prot:Q3T112

    Gene LinkOut

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