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    ST6GALNAC6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 [ Bos taurus (domestic cattle) ]

    Gene ID: 407222, updated on 28-Dec-2024

    Summary

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    Official Symbol
    ST6GALNAC6provided by VGNC
    Official Full Name
    ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6provided by VGNC
    Primary source
    VGNC:VGNC:35342
    See related
    Ensembl:ENSBTAG00000044129
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    siat7f; st6GalNAc-VI
    Orthologs
    human mouse all
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    Genomic context

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    See ST6GALNAC6 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (98555382..98573586, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene endoglin Neighboring gene adenylate kinase 1 Neighboring gene ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 Neighboring gene phosphatidylinositol-4-phosphate 5-kinase like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. Harduin-Lepers A, et al. Glycobiology, 2005 Aug. PMID 15843597
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC139767

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ganglioside biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oligosaccharide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
    Names
    SIAT7-F
    ST6GalNAc VI
    ST6GalNAcVI
    beta-galactosamide alpha-2,6-sialyltransferase
    galNAc alpha-2,6-sialyltransferase VI
    sialyltransferase 7F
    sialytransferase 7F
    NP_001001151.2
    XP_005213242.1
    XP_005213244.1
    XP_005213245.1
    XP_005213246.1
    XP_005213247.1
    XP_010808690.2
    XP_015329088.1
    XP_015329089.1
    XP_059747032.1
    XP_059747033.1
    XP_059747034.1
    XP_059747035.1
    XP_059747036.1
    XP_059747037.1
    XP_059747038.1
    XP_059747039.1
    XP_059747040.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001151.2 → NP_001001151.2  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

      See identical proteins and their annotated locations for NP_001001151.2

      Status: PROVISIONAL

      Source sequence(s)
      BC123467
      UniProtKB/Swiss-Prot
      Q08E15, Q704S2
      UniProtKB/TrEMBL
      A0A3Q1LQG5
      Related
      ENSBTAP00000057209.2, ENSBTAT00000083124.2
      Conserved Domains (1) summary
      pfam00777
      Location:101 → 322
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      98555382..98573586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010810388.4 → XP_010808690.2  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LQG5

    2. XM_005213188.5 → XP_005213245.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X5

      See identical proteins and their annotated locations for XP_005213245.1

      UniProtKB/TrEMBL
      A0A452DJH9
      Conserved Domains (1) summary
      pfam00777
      Location:68 → 289
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    3. XM_005213190.5 → XP_005213247.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X5

      See identical proteins and their annotated locations for XP_005213247.1

      UniProtKB/TrEMBL
      A0A452DJH9
      Conserved Domains (1) summary
      pfam00777
      Location:68 → 289
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    4. XM_059891054.1 → XP_059747037.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X5

      UniProtKB/TrEMBL
      A0A452DJH9

    5. XM_059891056.1 → XP_059747039.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X6

      UniProtKB/TrEMBL
      A0A452DJH9

    6. XM_059891055.1 → XP_059747038.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X6

      UniProtKB/TrEMBL
      A0A452DJH9

    7. XM_059891051.1 → XP_059747034.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X3

      UniProtKB/TrEMBL
      A0A452DJH9

    8. XM_005213187.5 → XP_005213244.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X5

      See identical proteins and their annotated locations for XP_005213244.1

      UniProtKB/TrEMBL
      A0A452DJH9
      Conserved Domains (1) summary
      pfam00777
      Location:68 → 289
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    9. XM_059891050.1 → XP_059747033.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X3

      UniProtKB/TrEMBL
      A0A452DJH9

    10. XM_015473602.3 → XP_015329088.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X5

      UniProtKB/TrEMBL
      A0A452DJH9
      Conserved Domains (1) summary
      pfam00777
      Location:68 → 289
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    11. XM_059891049.1 → XP_059747032.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X3

      UniProtKB/TrEMBL
      A0A452DJH9

    12. XM_015473603.3 → XP_015329089.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X5

      UniProtKB/TrEMBL
      A0A452DJH9
      Related
      ENSBTAP00000082192.1, ENSBTAT00000088674.1
      Conserved Domains (1) summary
      pfam00777
      Location:68 → 289
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    13. XM_005213189.5 → XP_005213246.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X5

      See identical proteins and their annotated locations for XP_005213246.1

      UniProtKB/TrEMBL
      A0A452DJH9
      Conserved Domains (1) summary
      pfam00777
      Location:68 → 289
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    14. XM_005213185.5 → XP_005213242.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X2

      UniProtKB/TrEMBL
      A0A452DJH9, A0AAA9T7J3
      Related
      ENSBTAP00000094711.1, ENSBTAT00000095062.1
      Conserved Domains (1) summary
      pfam00777
      Location:140 → 361
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    15. XM_059891053.1 → XP_059747036.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X5

      UniProtKB/TrEMBL
      A0A452DJH9
      Related
      ENSBTAP00000053714.4, ENSBTAT00000061027.4

    16. XM_059891057.1 → XP_059747040.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X7

    17. XM_059891052.1 → XP_059747035.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08E15.1 GenPept UniProtKB/Swiss-Prot:Q08E15

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