DARS1 aspartyl-tRNA synthetase 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: DARS1provided by VGNC
Official Full Name: aspartyl-tRNA synthetase 1provided by VGNC
Primary source: VGNC:VGNC:27881
See related: BGD:BT26801; EnsemblRapid:ENSBTAG00070001094
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: DARS; AspRS
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (61390819..61455933)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables aspartate-tRNA ligase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in aspartyl-tRNA aminoacylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of aminoacyl-tRNA synthetase multienzyme complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: aspartate--tRNA ligase, cytoplasmic

Names: aspartyl-tRNA synthetase, cytoplasmic

NP_001030257.1

EC 6.1.1.12

XP_059748842.1

EC 6.1.1.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001035085.1 → NP_001030257.1 aspartate--tRNA ligase, cytoplasmic

See identical proteins and their annotated locations for NP_001030257.1

Status: PROVISIONAL

Source sequence(s)

BC103319

UniProtKB/Swiss-Prot

Q3SYZ4

UniProtKB/TrEMBL

F1MTX7

Related

ENSBTAP00070001434.1, ENSBTAT00070002498.1

Conserved Domains (3) summary

PLN02850
Location:3 → 501

PLN02850; aspartate-tRNA ligase

cd00776
Location:174 → 497

AsxRS_core; Asx tRNA synthetase (AspRS/AsnRS) class II core domain. Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as ...

cd04320
Location:60 → 158

AspRS_cyto_N; AspRS_cyto_N: N-terminal, anticodon recognition domain of the type found in Saccharomyces cerevisiae and human cytoplasmic aspartyl-tRNA synthetase (AspRS). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop. ...