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    SLC39A8 solute carrier family 39 member 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 508193, updated on 4-Oct-2024

    Summary

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    Official Symbol
    SLC39A8provided by VGNC
    Official Full Name
    solute carrier family 39 member 8provided by VGNC
    Primary source
    VGNC:VGNC:34868
    See related
    BGD:BT14355; Ensembl:ENSBTAG00000005668
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SLC39A8 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (22459081..22542658)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene nuclear factor kappa B subunit 1 Neighboring gene uncharacterized LOC112447046 Neighboring gene 60S ribosome subunit biogenesis protein NIP7 homolog Neighboring gene uncharacterized LOC112447149 Neighboring gene ubiquitin-like-conjugating enzyme ATG10 Neighboring gene transfer RNA cysteine (anticodon ACA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Reproductive hormones influence zinc homeostasis in the bovine cumulus-oocyte complex: Impact on intracellular zinc concentration and transporters gene expression. Pascua AM, et al. Theriogenology, 2020 Apr 1. PMID 32036060
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables zinc ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular zinc ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in zinc ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    metal cation symporter ZIP8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205630.1 → NP_001192559.1  metal cation symporter ZIP8 precursor

      See identical proteins and their annotated locations for NP_001192559.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000006
      UniProtKB/TrEMBL
      E1BQ28
      Related
      ENSBTAP00000007448.5, ENSBTAT00000007448.6
      Conserved Domains (1) summary
      pfam02535
      Location:126 → 452
      Zip; ZIP Zinc transporter

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      22459081..22542658
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024993121.2 → XP_024848889.1  metal cation symporter ZIP8 isoform X1

      UniProtKB/TrEMBL
      E1BQ28
      Conserved Domains (1) summary
      pfam02535
      Location:126 → 452
      Zip; ZIP Zinc transporter

    2. XM_059887429.1 → XP_059743412.1  metal cation symporter ZIP8 isoform X2

    3. XM_024993122.2 → XP_024848890.1  metal cation symporter ZIP8 isoform X2

      Conserved Domains (1) summary
      pfam02535
      Location:55 → 381
      Zip; ZIP Zinc transporter
    Nucleotide Protein Strain
    Heading Accession and Version

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