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    TPR translocated promoter region, nuclear basket protein [ Bos taurus (domestic cattle) ]

    Gene ID: 507869, updated on 29-Jan-2025

    Summary

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    Gene symbol
    TPR
    Gene description
    translocated promoter region, nuclear basket protein
    See related
    BGD:BT16331; Ensembl:ENSBTAG00000060237
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TPR in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    52
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (67397882..67461760, complement)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene hemicentin 1 Neighboring gene V-type proton ATPase subunit e 1-like Neighboring gene histone H2B type 1-L-like Neighboring gene proteoglycan 4 Neighboring gene odr-4 GPCR localization factor homolog Neighboring gene phosducin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables structural constituent of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA export from nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein import into nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of mitotic spindle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nucleoprotein TPR
    Names
    translocated promoter region (to activated MET oncogene)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205623.1 → NP_001192552.1  nucleoprotein TPR

      See identical proteins and their annotated locations for NP_001192552.1

      Status: PROVISIONAL

      Source sequence(s)
      AAFC03110223, AAFC03113184
      UniProtKB/TrEMBL
      A0AAA9TLC7
      Related
      ENSBTAP00070017991.1, ENSBTAT00070029554.1
      Conserved Domains (5) summary
      COG1196
      Location:53 → 794
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR04527
      Location:962 → 1048
      mycoplas_twoTM; two transmembrane protein
      pfam00038
      Location:763 → 1085
      Filament; Intermediate filament protein
      pfam07851
      Location:1431 → 1506
      TMPIT; TMPIT-like protein
      pfam07926
      Location:1036 → 1164
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      67397882..67461760 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015475269.3 → XP_015330755.2  nucleoprotein TPR isoform X1

      UniProtKB/TrEMBL
      A0AAA9T4R9, A0AAA9TLC7
      Related
      ENSBTAP00070017967.1, ENSBTAT00070029495.1
      Conserved Domains (3) summary
      pfam07926
      Location:1117 → 1240
      TPR_MLP1_2; TPR/MLP1/MLP2-like protein
      cl25496
      Location:1724 → 1942
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cl25732
      Location:891 → 1693
      SMC_N; RecF/RecN/SMC N terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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