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    LRRC1 leucine rich repeat containing 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 506753, updated on 1-Jan-2025

    Summary

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    Official Symbol
    LRRC1provided by VGNC
    Official Full Name
    leucine rich repeat containing 1provided by VGNC
    Primary source
    VGNC:VGNC:30998
    See related
    BGD:BT28345; Ensembl:ENSBTAG00000017533
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LRRC1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (6593015..6727981, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene tubulointerstitial nephritis antigen Neighboring gene U6 spliceosomal RNA Neighboring gene muscular LMNA interacting protein Neighboring gene kelch like family member 31 Neighboring gene glutamate-cysteine ligase catalytic subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in embryo development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter receptor transport postsynaptic membrane to endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter receptor transport, endosome to postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in receptor clustering IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in basolateral plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205469.2 → NP_001192398.1  leucine-rich repeat-containing protein 1

      See identical proteins and their annotated locations for NP_001192398.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000023
      UniProtKB/TrEMBL
      A0A3Q1LTV0
      Related
      ENSBTAP00000060775.1, ENSBTAT00000073406.2
      Conserved Domains (3) summary
      cd00116
      Location:15 → 232
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:61 → 83
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:198 → 255
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      6593015..6727981 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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