U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    USP21 ubiquitin specific peptidase 21 [ Bos taurus (domestic cattle) ]

    Gene ID: 534273, updated on 30-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    USP21provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 21provided by VGNC
    Primary source
    VGNC:VGNC:52843
    See related
    BGD:BT18432; EnsemblRapid:ENSBTAG00070003087
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See USP21 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (8331475..8338162, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene beta-1,4-galactosyltransferase 3 Neighboring gene uncharacterized LOC132344819 Neighboring gene protoporphyrinogen oxidase Neighboring gene ubiquitin-fold modifier conjugating enzyme 1 Neighboring gene death effector domain containing Neighboring gene nitrilase 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC128708

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 21
    Names
    deubiquitinating enzyme 21
    ubiquitin thioesterase 21
    ubiquitin thiolesterase 21
    ubiquitin-specific-processing protease 21
    NP_001039841.1
    XP_024845232.1
    XP_059740685.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046376.2 → NP_001039841.1  ubiquitin carboxyl-terminal hydrolase 21

      See identical proteins and their annotated locations for NP_001039841.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105488
      UniProtKB/Swiss-Prot
      Q2KJ72
      Conserved Domains (2) summary
      cd02674
      Location:213 → 556
      Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam00443
      Location:212 → 555
      UCH; Ubiquitin carboxyl-terminal hydrolase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      8331475..8338162 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059884702.1 → XP_059740685.1  ubiquitin carboxyl-terminal hydrolase 21 isoform X1

      UniProtKB/TrEMBL
      F1MH36
      Related
      ENSBTAP00070004192.1, ENSBTAT00070007145.1

    2. XM_024989464.2 → XP_024845232.1  ubiquitin carboxyl-terminal hydrolase 21 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LYE6
      Related
      ENSBTAP00070004194.1, ENSBTAT00070007150.1
      Conserved Domains (1) summary
      pfam00443
      Location:212 → 526
      UCH; Ubiquitin carboxyl-terminal hydrolase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2KJ72.1 GenPept UniProtKB/Swiss-Prot:Q2KJ72

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials