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    KNTC1 kinetochore associated 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 506353, updated on 30-Jan-2025

    Summary

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    Official Symbol
    KNTC1provided by VGNC
    Official Full Name
    kinetochore associated 1provided by VGNC
    Primary source
    VGNC:VGNC:30699
    See related
    BGD:BT21752; EnsemblRapid:ENSBTAG00070011231
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See KNTC1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    65
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (52854276..52924766, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene ubiquitin Neighboring gene hydroxycarboxylic acid receptor 2 Neighboring gene arginine and serine rich coiled-coil 2 Neighboring gene zinc finger CCHC-type containing 8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic sister chromatid segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic spindle assembly checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to kinetochore involved in kinetochore assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RZZ complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in kinetochore microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kinetochore-associated protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192091.2 → NP_001179020.2  kinetochore-associated protein 1

      See identical proteins and their annotated locations for NP_001179020.2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000017
      UniProtKB/TrEMBL
      A0AAA9S4X0, E1BBQ0
      Related
      ENSBTAP00070015084.1, ENSBTAT00070025317.1
      Conserved Domains (1) summary
      pfam10493
      Location:1577 → 2126
      Rod_C; Rough deal protein C-terminal region

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      52854276..52924766 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005217760.5 → XP_005217817.1  kinetochore-associated protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005217817.1

      UniProtKB/TrEMBL
      A0AAA9S4X0, E1BBQ0
      Conserved Domains (1) summary
      pfam10493
      Location:1577 → 2126
      Rod_C; Rough deal protein C-terminal region

    2. XM_024977090.2 → XP_024832858.1  kinetochore-associated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S4X0, E1BBQ0
      Conserved Domains (1) summary
      pfam10493
      Location:1577 → 2126
      Rod_C; Rough deal protein C-terminal region

    3. XM_010813889.4 → XP_010812191.1  kinetochore-associated protein 1 isoform X1

      See identical proteins and their annotated locations for XP_010812191.1

      UniProtKB/TrEMBL
      A0AAA9S4X0, E1BBQ0
      Conserved Domains (1) summary
      pfam10493
      Location:1577 → 2126
      Rod_C; Rough deal protein C-terminal region

    4. XM_024977089.2 → XP_024832857.1  kinetochore-associated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S4X0, E1BBQ0
      Conserved Domains (1) summary
      pfam10493
      Location:1577 → 2126
      Rod_C; Rough deal protein C-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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