U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    VCL vinculin [ Bos taurus (domestic cattle) ]

    Gene ID: 783645, updated on 30-Jan-2025

    Summary

    Official Symbol
    VCLprovided by VGNC
    Official Full Name
    vinculinprovided by VGNC
    Primary source
    VGNC:VGNC:36779
    See related
    BGD:BT14271; EnsemblRapid:ENSBTAG00070028854
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See VCL in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (29876915..29989469)

    Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene calcium/calmodulin dependent protein kinase II gamma Neighboring gene plasminogen activator, urokinase Neighboring gene adaptor related protein complex 3 subunit mu 1 Neighboring gene adenosine kinase Neighboring gene axin interactor, dorsalization-associated protein-like

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC142547

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables alpha-catenin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables beta-catenin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cell-cell contact zone IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191370.1NP_001178299.1  vinculin

      See identical proteins and their annotated locations for NP_001178299.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000028
      UniProtKB/TrEMBL
      A0A3Q1LIB4
      Related
      ENSBTAP00070039803.1, ENSBTAT00070065725.1
      Conserved Domains (1) summary
      pfam01044
      Location:661134
      Vinculin; Vinculin family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      29876915..29989469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005226483.4XP_005226540.1  vinculin isoform X1

      See identical proteins and their annotated locations for XP_005226540.1

      UniProtKB/TrEMBL
      A0A3Q1LIB4
      Related
      ENSBTAP00070039865.1, ENSBTAT00070065788.1
      Conserved Domains (1) summary
      pfam01044
      Location:661066
      Vinculin; Vinculin family

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001078093.1: Suppressed sequence

      Description
      NM_001078093.1: This RefSeq was temporarily suppressed because the CDS was partial.