U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TINAG tubulointerstitial nephritis antigen [ Bos taurus (domestic cattle) ]

    Gene ID: 512517, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TINAGprovided by VGNC
    Official Full Name
    tubulointerstitial nephritis antigenprovided by VGNC
    Primary source
    VGNC:VGNC:35874
    See related
    Ensembl:ENSBTAG00000012652
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TINAG in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (6029291..6135380, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene family with sequence similarity 83 member B Neighboring gene U6 spliceosomal RNA Neighboring gene muscular LMNA interacting protein Neighboring gene leucine rich repeat containing 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC127400

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tubulointerstitial nephritis antigen
    Names
    TIN-Ag

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035107.2 → NP_001030279.1  tubulointerstitial nephritis antigen

      See identical proteins and their annotated locations for NP_001030279.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102843
      UniProtKB/Swiss-Prot
      Q3SZI1
      UniProtKB/TrEMBL
      A0A3Q1M5A7
      Related
      ENSBTAP00000016790.5, ENSBTAT00000016790.6
      Conserved Domains (3) summary
      cd02620
      Location:218 → 466
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      pfam01033
      Location:61 → 104
      Somatomedin_B; Somatomedin B domain
      cl17735
      Location:120 → 161
      VWC; von Willebrand factor type C domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      6029291..6135380 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005223240.5 → XP_005223297.1  tubulointerstitial nephritis antigen isoform X3

      UniProtKB/TrEMBL
      A0A3Q1M5A7
      Conserved Domains (2) summary
      cd02620
      Location:143 → 391
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      cl17735
      Location:45 → 86
      VWC; von Willebrand factor type C domain

    2. XM_010818036.3 → XP_010816338.1  tubulointerstitial nephritis antigen isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M5A7
      Conserved Domains (3) summary
      cd02620
      Location:218 → 467
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      pfam01033
      Location:61 → 104
      Somatomedin_B; Somatomedin B domain
      cl17735
      Location:120 → 161
      VWC; von Willebrand factor type C domain

    3. XM_010818037.3 → XP_010816339.1  tubulointerstitial nephritis antigen isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M5A7
      Conserved Domains (2) summary
      cd02620
      Location:143 → 392
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      cl17735
      Location:45 → 86
      VWC; von Willebrand factor type C domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3SZI1.1 GenPept UniProtKB/Swiss-Prot:Q3SZI1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials